JPRN-jRCTs072200027Recruiting未知
Instantaneous Wave-free Ratio and Fractional Flow Reserve Pullback Gradient to Guide Revascularization in Patients with Diffuse/tandem Coronary Lesions
Matsuo Hitoshi0 sites300 target enrollmentStarted: August 24, 2020Last updated:
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Recruiting
- Sponsor
- Enrollment
- 300
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- >= 20age old to ot applicable (—)
- Sex
- All
Inclusion Criteria
- •1.>20 years of age
- •2.Willing to participate and able to understand, read, and sign the informed consent document before the planned procedure
- •3.Eligible for coronary angiography and/or percutaneous coronary intervention
- •4.Patient with at least 2 separate (>10mm apart) or diffuse (>20mm) de novo angiographically 50-90% stenoses in one native major epicardial vessel or their major branches (The stenosis will be regarded as single when the gap is 10mm or shorter between the 2 narrowings)
- •5.Single coronary artery disease
- •6.Stable coronary artery disease (with or without a history of PCI)
Exclusion Criteria
- •1.Previous CABG with patent grafts to the interrogated vessel
- •2.Total coronary occlusions
- •3.Cardiogenic shock, or intra-aortic balloon pumping
- •4.Contraindications to PCI or drug-eluting stent (DES) implantation
- •5.Malignant disease with unfavorable prognosis that may influence survival within the next 3 years
- •6.EF < 30%
- •7.eGFR < 15mL/min/1.73m2
- •8.Pregnant or planning to be pregnant
- •9.Frequent arrhythmia
- •10.Acute coronary syndrome or a history of myocardial infarction
- •11.Severe valvular heart disease
- •12.Distal coronary disease < 2.5 mm by visual estimation
- •13.Baseline flow < TIMI 3 or intracoronary thrombus
- •14.Included in other intervention trials
- •15.Weight > 200kg
- •16.Severe allergy to contrast media
- •17.Contraindications to antithrombotic therapy
Investigators
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