Myocardial and Renal Dysfunction by Oxidative Stress Caused by Cardiac Surgery
Terminated
- Conditions
- Reperfusion Injury
- Registration Number
- NCT02394405
- Lead Sponsor
- Moscow Regional Research and Clinical Institute (MONIKI)
- Brief Summary
Assessment of the severity of oxidative stress caused by the on-pump and off-pump cardiac surgery using mtDNA, nDNA, carbonilated proteins, nitrotyrosine, oxy-LDL, S100b-protein.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 21
Inclusion Criteria
- shedduled CABG
Exclusion Criteria
- stroke befor surgery
- miocardial infarction 6 monthes befor surgery
- dementia
- liver cirrhosis
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assay of mtDNA from baseline whithin 72 hours
- Secondary Outcome Measures
Name Time Method Assay of S100b-protein from baseline whithin 72 hours Assay of nDNA from baseline whithin 72 hours Assay of carbonilated proteins from baseline whithin 72 hours Assay of nitrotyrosine from baseline whithin 72 hours Assay of oxy-LDL from baseline whithin 72 hours
Trial Locations
- Locations (1)
Moscow Regional Research and Clinical Institute Moniki n.a. M.F. Vladimirskiy
🇷🇺Moscow, Russian Federation
Moscow Regional Research and Clinical Institute Moniki n.a. M.F. Vladimirskiy🇷🇺Moscow, Russian Federation