NCT02394405终止不适用
Myocardial and Renal Dysfunction by Oxidative Stress Caused by Cardiac Surgery
Moscow Regional Research and Clinical Institute (MONIKI)1 个研究点 分布在 1 个国家目标入组 21 人开始时间: 2015年3月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- Assay of mtDNA
研究概览
简要总结
Assessment of the severity of oxidative stress caused by the on-pump and off-pump cardiac surgery using mtDNA, nDNA, carbonilated proteins, nitrotyrosine, oxy-LDL, S100b-protein.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •shedduled CABG
排除标准
- •stroke befor surgery
- •miocardial infarction 6 monthes befor surgery
- •liver cirrhosis
结局指标
主要结局
Assay of mtDNA
时间窗: from baseline whithin 72 hours
次要结局
- Assay of S100b-protein(from baseline whithin 72 hours)
- Assay of nDNA(from baseline whithin 72 hours)
- Assay of carbonilated proteins(from baseline whithin 72 hours)
- Assay of nitrotyrosine(from baseline whithin 72 hours)
- Assay of oxy-LDL(from baseline whithin 72 hours)
研究者
Valery V. Likhvantsev, Professor
senior researcher
Moscow Regional Research and Clinical Institute (MONIKI)
研究点 (1)
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