跳至主要内容
临床试验/NCT06391866
NCT06391866招募中不适用

Assessing Neuroinflammation and Oxidative Stress After Cardiac Surgery: Unveiling Molecular Dynamics and Clinical Outcomes

Europainclinics z.ú.1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年4月30日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
60
试验地点
1
主要终点
Number and type of early complications after surgery

研究概览

简要总结

The prospective observational study delves into the complex relationship between neuroinflammation and oxidative stress in post-cardiac surgery complications, focusing on postoperative cognitive dysfunction.

详细描述

The prospective observational study meticulously examines the interplay between neuroinflammation and oxidative stress in the realm of post-cardiac surgery complications, specifically targeting postoperative cognitive dysfunction. Its primary objective is to comprehensively assess the sustained influence of these intricate processes on cognitive function and overall well-being, extending beyond the immediate aftermath of surgery. The research endeavors to probe deeply into the molecular mechanisms and clinical ramifications associated with neuroinflammation and oxidative stress, centering on their pivotal role in shaping the onset and trajectory of postoperative cognitive dysfunction.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Undergoing cardiosurgical operation
  • Absence of previous neurological disease
  • Signed informed consent document

排除标准

  • Presence of neoplasms
  • Neurological Disease
  • Refusal to participate in the clinical trial

结局指标

主要结局

Number and type of early complications after surgery

时间窗: 1 month

Estimating of postoperative complications

Number and type of postoperative complications

时间窗: 6 months

Estimating of postoperative complications

次要结局

  • Estimating biochemical parameters Third biochemical examination(1 hour)
  • Estimating biochemical parameters(6 hours)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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