跳至主要内容
临床试验/CTRI/2024/11/077240
CTRI/2024/11/077240尚未招募不适用

Comparison of the efficacy of ondansetron alone versus ondansetron and dexamethasone in the prevention or reduction of post operative nausea and vomiting after elective surgeries under general anaesthesia

Dr Juhi Mishra1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2024年11月30日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
100
试验地点
1
主要终点
To compare the post operative analgesic effects between ondansetron and ondansetron with dexamethasone

研究概览

简要总结

The study is designed to provide evidence that may guide clinical decision-making in managing PONV, potentially improving patient comfort and recovery outcomes. If the combination therapy proves to be more effective than ondansetron alone, it could become the preferred treatment option for preventing PONV in this patient population. Conversely, if both regimens show similar efficacy, the simpler treatment of ondansetron alone may be sufficient, with implications for reducing treatment costs and minimizing medication-related side effects.

This study seeks to add valuable insights into the optimal management strategies for PONV, contributing to enhanced patient care following elective surgeries

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.Able to provide informed consent 2.American Society of Anaesthesiologists (ASA) physical status I and II.

排除标准

  • Patients with contraindications to either medication Patients requiring emergency surgery or those undergoing surgeries with known high PONV risk Severe cardiorespiratory hepatic renal neurological or endocrinal disease obesity diabetes mellitus.

结局指标

主要结局

To compare the post operative analgesic effects between ondansetron and ondansetron with dexamethasone

时间窗: 2hours 6hours 12hours 24hours

次要结局

  • To identify any potential predictors of optimal dose selection and see the efficacy of both drugs in full 24 hours(2hours 6hours 12hours 24hours)

研究者

发起方
Dr Juhi Mishra
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Juhi Mishra

Varun arjun medical college and rohilkhand hospital

研究点 (1)

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