Comparison of the efficacy of ondansetron alone versus ondansetron and dexamethasone in the prevention or reduction of post operative nausea and vomiting after elective surgeries under general anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To compare the post operative analgesic effects between ondansetron and ondansetron with dexamethasone
研究概览
简要总结
The study is designed to provide evidence that may guide clinical decision-making in managing PONV, potentially improving patient comfort and recovery outcomes. If the combination therapy proves to be more effective than ondansetron alone, it could become the preferred treatment option for preventing PONV in this patient population. Conversely, if both regimens show similar efficacy, the simpler treatment of ondansetron alone may be sufficient, with implications for reducing treatment costs and minimizing medication-related side effects.
This study seeks to add valuable insights into the optimal management strategies for PONV, contributing to enhanced patient care following elective surgeries
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •1.Able to provide informed consent 2.American Society of Anaesthesiologists (ASA) physical status I and II.
排除标准
- •Patients with contraindications to either medication Patients requiring emergency surgery or those undergoing surgeries with known high PONV risk Severe cardiorespiratory hepatic renal neurological or endocrinal disease obesity diabetes mellitus.
结局指标
主要结局
To compare the post operative analgesic effects between ondansetron and ondansetron with dexamethasone
时间窗: 2hours 6hours 12hours 24hours
次要结局
- To identify any potential predictors of optimal dose selection and see the efficacy of both drugs in full 24 hours(2hours 6hours 12hours 24hours)
研究者
Dr Juhi Mishra
Varun arjun medical college and rohilkhand hospital
