CTRI/2022/08/045087
Recruiting
未知
Assessing the impact of radiation dose exposure to lung and heart on effort tolerance
MAHE Manipal0 sites0 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: - Health Condition 2: J99- Respiratory disorders in diseasesclassified elsewhere
- Sponsor
- MAHE Manipal
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients being planned for definitive or adjuvant thoracic radiotherapy that involves direct radiation exposure to at least a part of heart and lungs.
- •2\. Good performance score (KPS \>\=70\), and ability to perform the physical tests required for assessment.
- •3\. Adequate baseline hematocrit, and cardiac and pulmonary function. Estimated life expectancy of at least 12 months.
- •4\. Willing to participate in the study, and provides voluntary informed consent
Exclusion Criteria
- •1\.KPS \<70\.
- •2\.Patients being treated with extreme hypofractionated regimen, mainly SBRT.
- •3\.Other comorbidities such as Chronic Lung disease, cardiac disease, anemia at presentation, chronic kidney disease, peripheral neuropathy, disabilities in ambulation, etc., that might interfere with the conduct of the physical assessments.
- •4\.Baseline impairment in respiratory or cardiac function as an indirect result of the tumor; eg. Lobar/pulmonary collapse secondary to obstructing tumor, pleural or pericardial effusion, etc.
Outcomes
Primary Outcomes
Not specified
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