Long-term Follow-up and Treatment Protocol for Craniofacial Fibrous Dysplasia From 40-year Data at Chang Gung Memorial Hospital: A Retrospective Case Series
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 13
- 试验地点
- 1
- 主要终点
- Recurrence
研究概览
简要总结
Craniofacial fibrous dysplasia (CFD) is a nonneoplastic disease characterized by fibro-osseous lesions in the affected bones. Treatment is mainly surgical and is stratified based on four different anatomical zones. This study aimed to evaluate the long-term outcomes and refine the algorithm for CFD.
详细描述
According to Chen et. al for the appropriate surgical management of FD the craniofacial skeleton can be divided into four zones according to the consideration of facial cosmesis, vital anatomical region and function preserving. The aim of the study was to evaluate the outcome of nearly 40 years long-term follow up cohort group and refine the algorithm of surgical intervention of FD under 4 zones classification.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Received CFD surgical intervention between 1972 and 2019
- •Personal interviews: between late 2019 and 2020, covering a postoperative period of over 20 years
- •All the surgery were performed by a senior surgeon (Yu-Ray Chen) at Chang Gung Craniofacial Center
排除标准
- •Patients who underwent surgical treatment at other institutions during the follow-up period or those who did not return to the craniofacial outpatient department for follow-up and receive computed tomography scans between 2019 and 2020 will be excluded.
结局指标
主要结局
Recurrence
时间窗: Personal interviews with facial bone computed tomography obtained on late 2019 and 2020
Recurrence based on facial bone computed tomography
次要结局
未报告次要终点
研究者
Pangyunchou
Associate Professor
Chang Gung Memorial Hospital