Treatment Protocol and Long-Term Outcomes in Craniofacial Fibrous Dysplasia
- Conditions
- Craniofacial Fibrous Dysplasia
- Registration Number
- NCT06167122
- Lead Sponsor
- Chang Gung Memorial Hospital
- Brief Summary
Craniofacial fibrous dysplasia (CFD) is a nonneoplastic disease characterized by fibro-osseous lesions in the affected bones. Treatment is mainly surgical and is stratified based on four different anatomical zones. This study aimed to evaluate the long-term outcomes and refine the algorithm for CFD.
- Detailed Description
According to Chen et. al for the appropriate surgical management of FD the craniofacial skeleton can be divided into four zones according to the consideration of facial cosmesis, vital anatomical region and function preserving. The aim of the study was to evaluate the outcome of nearly 40 years long-term follow up cohort group and refine the algorithm of surgical intervention of FD under 4 zones classification.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 13
- Received CFD surgical intervention between 1972 and 2019
- Personal interviews: between late 2019 and 2020, covering a postoperative period of over 20 years
- All the surgery were performed by a senior surgeon (Yu-Ray Chen) at Chang Gung Craniofacial Center
- Patients who underwent surgical treatment at other institutions during the follow-up period or those who did not return to the craniofacial outpatient department for follow-up and receive computed tomography scans between 2019 and 2020 will be excluded.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Recurrence Personal interviews with facial bone computed tomography obtained on late 2019 and 2020 Recurrence based on facial bone computed tomography
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Chang Gung Memorial Hospital
🇨🇳Taoyuan, Taiwan
Chang Gung Memorial Hospital🇨🇳Taoyuan, Taiwan