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临床试验/NCT00853281
NCT00853281已完成不适用

A Cluster Randomized Trial to Evaluate the Effectiveness of Long Lasting Insecticidal Hammocks for Controlling Forest Malaria in Central Vietnam

Institute of Tropical Medicine, Belgium1 个研究点 分布在 1 个国家目标入组 18,646 人开始时间: 2004年3月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
18,646
试验地点
1
主要终点
Reduction of malaria prevalence and incidence

研究概览

简要总结

In Central Vietnam, forest malaria remains difficult to control due to the complex interactions between human, vector and environmental factors. Untreated bednets had a significantly protecting effect for villagers, except for those regularly sleeping in the forest, who suffer a significantly higher number of clinical attacks. Thus, there is need to target this high-risk group with new intervention based on long-lasting insecticidal materials. Hammocks are extensively used by people working in the forest, therefore long-lasting insecticidal hammocks (LLIH) could achieve a good individual protection.

The Investigators proposed to evaluate their effectiveness in a community-based trial, comparing them to the standard vector control methods (insecticide-treated nets).

详细描述

In Central Vietnam, forest malaria remains difficult to control due to the complex interactions between human, vector and environmental factors. A community-based study carried out between 1999 and 2001 showed that regular forest activity was a strong risk factor for malaria infection. Untreated bednets had a significantly protecting effect for villagers, except for those regularly sleeping in the forest, who suffered a significantly higher number of clinical attacks. Thus, there is need to target this high-risk group with new intervention based on long-lasting insecticidal materials. Hammocks are extensively used by people working in the forest, therefore long-lasting insecticidal hammocks (LLIH) could achieve a good individual protection.

The Investigators proposed to evaluate their effectiveness in a community-based trial, comparing them to the standard vector control methods (insecticide-treated nets): communities have been grouped into clusters of about 1000 înhabitants, and clusters were randomized to either the active intervention or the active control, and followed up for 24 month.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • All residents in the 20 concerned study clusters and willing to give informed consent to participate

排除标准

  • People not willing to give informed consent to participate

结局指标

主要结局

Reduction of malaria prevalence and incidence

时间窗: 24 months

次要结局

  • Reduction of malaria sero-prevalence(24 months)

研究者

发起方
Institute of Tropical Medicine, Belgium
申办方类型
Other

研究点 (1)

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