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Clinical Trials/NCT04227860
NCT04227860
Completed
N/A

The Effect of Combined Balance and Strength Exercise Program in Patients With Different Grades of Primary Knee Osteoarthritis Patients

University of Alexandria1 site in 1 country80 target enrollmentJanuary 20, 2020

Overview

Phase
N/A
Intervention
Not specified
Conditions
Knee Osteoarthritis
Sponsor
University of Alexandria
Enrollment
80
Locations
1
Primary Endpoint
Assessment of pain
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The aim of this study is to assess the effect of balance exercise on dynamic balance and physical function in 80 patients with different grades of primary knee osteoarthritis (KOA).

Detailed Description

The study will include 80 patients with primary knee osteoarthritis divided into 4 groups according to the Kellgren and Lawrence grading scale (KL): Group 1: 20 patients with grade I KOA Group 2: 20 patients with grade II KOA Group 3: 20 patients with grade III KOA Group 4: 20 patients with grade IV KOA * Patients will undergo pre-exercise and post- exercise assessment with: 1. Western Ontario and McMaster University Osteoarthritis Index (WOMAC) 2. Modified Stare Excursion Balance test 3. Timed up and Go test * Exercise program includes: 1. Lower extremity kinesthesia and balance exercise program 2. Strength exercise program

Registry
clinicaltrials.gov
Start Date
January 20, 2020
End Date
December 31, 2021
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Yousra Hisham Abdel Fattah

Lecturer of Physical Medicine, Rheumatology and Rehabilitation

University of Alexandria

Eligibility Criteria

Inclusion Criteria

  • Patients with primary knee osteoarthritis according to the EULAR recommendations
  • Patients can complete at least stage 1 of balance and exercise program (minimum of 2 weeks)

Exclusion Criteria

  • Patients that cannot complete at least stage 1 of balance and exercise program
  • Patients with medical conditions affecting postural balance including visual, inner ear and neurological problems.
  • Patients with lower limb joint or bony problems other than primary knee osteoarthritis .
  • Patients with secondary KOA.
  • Patients who received intra- articular joint injection in 1 or both knees in the past 90 days.

Outcomes

Primary Outcomes

Assessment of pain

Time Frame: 2-6 weeks

Using the Western Ontario and McMaster University Osteoarthritis Index (WOMAC), which contains pain sub-score and a overall total score. The higher the score the worst the pain.

Assessment of stiffness

Time Frame: 2-6 weeks

Using the Western Ontario and McMaster University Osteoarthritis Index (WOMAC), which contains stiffness sub-score and a overall total score. The higher the score the worst the stiffness.

Assessment of physical function

Time Frame: 2-6 weeks

Using the time up and go test, where the patient is seated and asked to get up walk a distance turn around and return to chair and sit again. It is measured using a timer, the longer the patient takes the worst the physical function of the patient.

Secondary Outcomes

  • Dynamic Balance(2-6 weeks)

Study Sites (1)

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