A study to observe accuracy of variation in the diameter with breathing of two large vein for predicting decrease in blood pressure after anaesthesia.
- Conditions
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified,
- Registration Number
- CTRI/2020/12/029511
- Lead Sponsor
- All India Institute of Medical Sciences
- Brief Summary
Ultrasound (US) guided measurement of inferior vena cava (IVC) diameter and it’s respiratory variability i.e collapsibility index (CI) has been shown to predict the post induction hypotension with high sensitivity and specificity. However, in conditions like pregnancy, abdominal distension, obesity etc it is difficult to scan the IVC and to assess the volume status. The role of US guided measurements of other central veins like internal jugular vein, femoral vein etc in predicting the volume status were also evaluated. The diagnostic accuracy for them was found to be inferior to the IVC. Recently, the sub clavian vein (SCV) CI during deep inspiration was shown to predict the post induction hypotension. In the available literature there is no head to head comparison of IVC and SCV for prediction of post induction hypotension. Therefore in our study we will compare the diagnostic accuracy of US guided measurement of IVC and SCV parameters during quiet and deep breathing for predicting post induction hypotension. We hypothesize that there will be no difference between the diagnostic accuracy of SCV- CI and IVC-CI for prediction of post induction hypotension.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 130
Patients of either sex of age 18 to 85 years and scheduled for elective surgery under general anesthesia.
Autonomic nervous system disorders Implanted pacemaker/ cardioverter Mental incompetence/ non cooperation Pregnancy.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare diagnostic accuracies of SCV-CI and IVC-CI for prediction of post induction hypotension during quiet breathing. From Induction of Anaesthesia till 20 minutes after induction
- Secondary Outcome Measures
Name Time Method 1.To compare the diagnostic accuracies of SCV-CI and IVC-CI for prediction of post induction hypotension during deep breathing. 2.Time needed to acquire ultrasound images and measure venous diameter,
Trial Locations
- Locations (1)
All India Institute of Medical Sciences
🇮🇳Jodhpur, RAJASTHAN, India
All India Institute of Medical Sciences🇮🇳Jodhpur, RAJASTHAN, IndiaGaurav ChaudharyPrincipal investigator9711371496garvjipmer@gmail.com