Investigating the effect of adding traditional medicine treatments (honey and frankincense extract) to common treatments on polyuria in patients with diabetes insipidus
Phase 2
- Conditions
- neurogenic diabetes insipidus due to brain diseases or head injury.Diabetes insipidusE23.2
- Registration Number
- IRCT20221121056570N1
- Lead Sponsor
- Ahvaz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Hospitalization in the intensive care unit
Having diagnostic criteria for diabetes insipidus
Signing the informed consent form by the patient's family
Establishment of enteral nutrition
Not having drug interactions with the drugs received by the patient based on the opinion of traditional medicine pharmacist colleagues
Exclusion Criteria
Discontinuation of enteral feeding for any reason
Death of the patient due to various causes
Patient discharge
Declaration of non-consent by the patient's family to continue the plan
The occurrence of drug interactions with the drugs received by the patient based on the opinion of traditional medicine pharmacist colleagues
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Patient's urine volume during 24-hour. Timepoint: 24-hour urine volume measurement at the beginning of the study (before the start of the intervention) and 24 and 48 and 72 hours after the administration of placebo, honey-frankincense or honey-ginger combination. Method of measurement: 24-hour urine volume measurement by graduated urine bags connected to the patient's Foley catheter daily (every 24 hours).
- Secondary Outcome Measures
Name Time Method Serum sodium level. Timepoint: Serum sodium level measurement at the beginning of the study (before the start of the intervention) and 24 and 48 and 72 hours after the administration of placebo, honey-frankincense or honey-ginger combination. Method of measurement: Laboratory measurement on blood sample by biochemistry autoanalyzer.