Influence of Bilateral Cervical Manipulation (C3/C4) on Thoracoabdominal Kinematics on Healthy Young Adults: Randomized Controlled Trial (RCT)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 90
- 试验地点
- 2
- 主要终点
- Change from Baseline in anterior-to-posterior of the abdomen right after the intervention
研究概览
简要总结
There is evidence of the interdependence between the diaphragm and the C4 vertebral level with regard to nerve, fascial and muscular connections. The purpose of this study is to evaluate the influence of cervical bilateral manipulation (C3/C4) on the thoracoabdominal kinematics in healthy young adults.
详细描述
Due to respiration the thoracoabdominal kinematics is considered a complex mechanism that evolves the movement of the ribs and fascia, the diaphragmatic function, the respiratory muscles and the mechanical properties of the airways that includes a coordinated reflex neural activity. The phrenic nerve (C3 to C5) is responsable for the motor and sensory innervation of the diaphragm.
The High Velocity Low Amplitude (HVLA) vertebral manipulation stimulates the corresponding spinal nerves. It is well known that when this manipulation is applied to cervical region induces vasomotor cutaneous and cardiorespiratory modifications in autonomic nervous system.
The sample composed of healthy young adults (aged 18-40 years) will be assigned randomly in three groups: experimental group (bilateral C3/C4 HVLA manipulation), sham manipulation group (passive cervical mobilization) and control group (no intervention). The thoracoabdominal kinematics measures will be assessed at baseline, right after the intervention and five minutes after the second measure using the Qualisys Motion Capture System.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Volunteers between 18 and 40 years of age.
排除标准
- •Attending a degree in Osteopathy or being a health professional in this area;
- •Apprehension to cervical manipulation;
- •Be pregnant;
- •Presenting cervical pain on the day of the study;
- •Does not comply with the Australian Vertebral Artery Protocol guidelines;
- •Having a clinical history of cervical and/or thoracoabdominal surgery;
- •Having a clinical history of cervical trauma during the prior 12 months;
- •Recurrent use of anti-coagulant and/or analgesic, muscle relaxant or anti-inflammatory therapeutics during the week before the study;
- •Have been submitted to any manual intervention at cervical region during the week before the study;
- •Having cardio-respiratory, neurological, rheumatic, oncologic and/or systemic diagnosed pathologies.
结局指标
主要结局
Change from Baseline in anterior-to-posterior of the abdomen right after the intervention
时间窗: Immediately after the intervention
The Qualysis Motion Capture System will measure the variation of the tridimensional movement of the abdomen through the positioning of two reflectors that will be placed in standardized points: in the umbilicus and the spinal process of L3. The volunteer will be seated with 110º of hip and knee flexion using a digital goniometer and will be asked to breath normally for 90 seconds. This measure instrument have eight infrared cameras which after the calibration process will determine the data of the tridimensional thoracoabdominal amplitude variations of the volunteer by the kinematic of the reflex markers.
Change from Baseline in anterior-to-posterior of the abdomen 5 minutes after the intervention
时间窗: 5 minutes after the intervention
The Qualysis Motion Capture System will measure the variation of the tridimensional movement of the abdomen through the positioning of two reflectors that will be placed in standardized points: in the umbilicus and the spinal process of L3. The volunteer will be seated with 110º of hip and knee flexion using a digital goniometer and will be asked to breath normally for 90 seconds. This measure instrument have eight infrared cameras which after the calibration process will determine the data of the tridimensional thoracoabdominal amplitude variations of the volunteer by the kinematic of the reflex markers.
次要结局
- Change from Baseline in anterior-to-posterior of the upper ribcage right after the intervention(Immediately after the intervention)
- Change from Baseline in anterior-to-posterior of the upper ribcage 5 minutes after the intervention(5 minutes after the intervention)
- Change from Baseline in medial-to-lateral of the lower ribcage right after the intervention(Immediately after the intervention)
- Change from Baseline in medial-to-lateral of the lower ribcage 5 minutes after the intervention(5 minutes after the intervention)
研究者
Natália Maria Oliveira Campelo
Professor
Escola Superior de Tecnologia da Saúde do Porto