NCT00449631已完成不适用
Multidrug Resistance After Trabeculectomy With Mitomycin C
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
研究概览
简要总结
We investigate whether mitomycin C treatment during previous filtration surgery induces P-glycoprotein expression.
详细描述
Despite the adjuvant use of mitomycin C during trabeculectomy, short-term and long-term failures still occur. We investigate whether mitomycin C treatment during previous trabeculectomy induces P-glycoprotein expression. Expression of P-glycoprotein is analysed in surgically removed Tenon tissue using immunohistochemistry.
研究设计
- 研究类型
- Observational
- 时间视角
- Other
入排标准
- 年龄范围
- 8 Years 至 85 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with planned trabeculectomy for elevated eye pressure
- •one third of patients without previous trabeculectomy
- •two thirds of patients with previous trabeculectomy (one third with and one third without the use of mitomycin C)
排除标准
- •patients not requiring surgery
- •patients with planned surgery for elevated eye pressure other than trabeculectomy
研究者
研究点 (1)
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