Pilot study to reduce anticholinergic load
- Conditions
- Drug therapy safety
- Registration Number
- DRKS00012346
- Lead Sponsor
- Abteilung Klinische Pharmakologie und Pharmakoepidemiologie, Medizinische Klinik
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Patient admitted to the Geriatric Rehabilitation of the Agaplesion Bethanien Hospital in Heidelberg; Age = 65 years;
Taking at least one strong anticholinergic drug on a regular basis (this condition does not affect the comparison group);
cognitive and physical stable to participate in the study
Exclusion Criteria
Mental or physical condition which does not allow the study participation; Particularly, patients with stroke, postoperative delirium, or dementia are excluded; Missing informed consent
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Development and testing of different models for predicting anticholinergic load (time point of analysis: study end); Examination of the practicability of the decision aid for reducing anticholinergic load via feedback questionnaires of the participating physicians (time point of examination: during study).
- Secondary Outcome Measures
Name Time Method Characterization of patients with different anticholinergic loads by cognition tests as well as by the assessment of anticholinergic adverse drug reactions at admission and approximately 14 days later (time of examination: during study).