HYPERTENSIVE CRISIS AND ATMOSPHERIC PRESSURE RELATIONSHIP

Recruiting

• Conditions: Hypertensive Urgency; Weather

• Registration Number: NCT06635603
• Lead Sponsor: Saglik Bilimleri Universitesi

Brief Summary

relationship between the onset times of symptoms and the regions of patients presenting to the emergency department with hypertensive crisis (systolic ≥180 and/or diastolic ≥110 mmHg) and the fluctuations in atmospheric pressure

Detailed Description

Hypertensive emergency is defined as grade 3 hypertension (systolic ≥180 and/or diastolic ≥110 mmHg) that causes end-organ damage, requiring urgent intervention and intensive care admission . Hypertensive crisis is described as severe hypertension not associated with end-organ damage. Some sources define hypertensive crisis as hypertension of grade 3 or higher, while others refer to it as severe hypertension without specifying a threshold .

Literature reviews, published guidelines, and studies indicate that the definitions and treatment approaches for hypertensive crisis differ between Europe and America, with variations in management from one physician to another . Seasonal blood pressure fluctuations are influenced by external temperature, indoor temperature, humidity, atmospheric pressure, and wind . Notably, during periods of low atmospheric pressure, blood pressure measurements show statistically significant increases compared to other days . Consequently, the frequency of life-threatening conditions associated with hypertension, such as intracranial hemorrhage and abdominal aortic aneurysm rupture, has been observed to increase on days when atmospheric pressure changes .

In our study, we aim to investigate the relationship between the onset times of symptoms and the regions of patients presenting to the emergency department with hypertensive crisis (systolic ≥180 and/or diastolic ≥110 mmHg) and the fluctuations in atmospheric pressure

Study Timeline

• Study Start: 2024-09-15
• Status Verified: 2024-10
• Study First Submitted: 2024-10-08
• Study First Submitted QC: 2024-10-08
• Last Update Submitted: 2024-10-08
• Study First Posted: 2024-10-10
• Last Update Posted: 2024-10-10
• Primary Completion: 2025-09-15
• Study Completion: 2025-09-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 350

Inclusion Criteria

1. Age 18 and above
2. Hypertensive crisis (systolic ≥180 and/or diastolic ≥110 mmHg)

Exclusion Criteria

1. Patients presenting with hypertensive emergency (those with end-organ damage)
2. Patients who have traveled to another city or district within the last 4 days
3. Pregnant patients

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hypertensive Crisis	from enrollment to the end of follow up duration of 7 days	Patients' blood pressure values evaluation in terms of atmospheric pressure and weather conditions

Trial Locations

Locations (1)

Etlik City Hospital; 🇹🇷 Ankara, Turkey