CTRI/2024/12/078320尚未招募不适用
Predictive relevance of preoperative Controlling Nutritional Status Score in children undergoing congenital cardiac surgery
DR VENUTHURUPALLI S P RAJESH1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2024年12月31日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- We hypothesise that the scores at hospital presentation can predict in hospital prognosis of the patient with congenital cardiac disease independently of other known prognostic factor.
研究概览
简要总结
- Despite recent advances in congenital cardiac surgery, there remain unmet need to reduce the high mortality rate and to assess the mortality risk in post operativeperiod. Recently, there was a line of evidences that nutritional status has a link to the prognosis of patients. Malnutrition is related to altered intestinal function, which could be due to hemodynamic changes. Intestinal congestion leads to bowel edema and overgrowth of bacteria flora, resulting in malabsorption, chronic inflammation, and malnutrition. The Controlling Nutritional Status (CONUT) score is a screening tool to identify undernourished patients in the hospitalized population. The score is derived from the values of serum albumin, total cholesterol and lymphocyte counts. Albumin represents the protein reserves; total cholesterol represents caloric depletion; and lymphocyte count represents immune defense. The decrease in each component was assigned with high score. Thus, the higher score means the worse nutritional status.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 6.00 Month(s) 至 18.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients undergoing Cardiac Surgery under Cardiopulmonary Bypass.
排除标准
- •Patients aged less than 6 months, Patients aged more than 18 years, Preterm patients, Patients with preoperative sepsis, Patients requiring preoperative Mechanical Ventilation.
结局指标
主要结局
We hypothesise that the scores at hospital presentation can predict in hospital prognosis of the patient with congenital cardiac disease independently of other known prognostic factor.
时间窗: At hospital presentation, Postoperative day 1, Postoperative day 2, day of extubation, day of shifting to ward from the ICU.
次要结局
- Relation of CONUT to sepsis & prolonged hospital stay.(Day of presentation to the hospital, day of surgery, postoperative day 1, postoperative day 2, day of extubation, day of shifting from the ICU to the ward.)
研究者
Dr Venuthurupalli S P Rajesh
UN Mehta Institute of Cardiology and Research Centre.
研究点 (1)
Loading locations...
相似试验
尚未招募
不适用
Preventing Neurologic Complications in Valve SurgeryNCT07382362China National Center for Cardiovascular Diseases100
尚未招募
2 期
A study on the comparison between nebulization with ketamine and magnesium sulfate before the surgery in the prevention of after an operation sorethroat in patients going through general anaesthesia(putting the patient to sleep with medicine) with endotracheal intubation(breathing tube in throat)CTRI/2025/09/095191Department of Anaesthesia70
招募中
不适用
Multicenter Randomized Controlled Trial (RCT) and Efficacy Evaluation System Study on Surgical Innovation Strategies for Neonatal Complex Congenital Heart DiseaseNCT07363538Central China Fuwai Hospital of Zhengzhou University738
尚未招募
不适用
Cardiovascular Surgery Early Prediction System for AKI :CARDS-AKI RegistryNCT07330453Chinese Academy of Medical Sciences, Fuwai Hospital5,000
Enrolling By Invitation
不适用
Early Detection of Brain Injury After Congenital Heart Surgery in InfantsNCT07424976University Medical Centre Ljubljana30