Microcirculation of the Abdominal Skin After Deep Inferior Epigastric Artery Perforator Flap Procedure

Completed

• Conditions: Skin Perfusion; Breast Reconstruction
• Interventions: Device: Laser Doppler perfusion imaging

• Registration Number: NCT02481284
• Lead Sponsor: Oslo University Hospital

Brief Summary

The purpose of this study was to perform a quantitative perfusion study of the undermined abdominal skin in deep inferior epigastric artery perforator flap breast reconstruction patients in order to obtain more knowledge on perfusion dynamics. Laser Doppler perfusion imaging (LDPI) was used to evaluate this.

Microcirculatory changes were monitored in the abdominal skin of 20 consecutive patients. Measurements were taken and recorded within four standardized zones covering the skin between the xiphoid process and the upper incisional boundary of the flap (zone 1-4; cranial to caudal).

Detailed Description

Background: No studies have assessed the perfusion of the undermined abdominal skin in breast reconstruction with deep inferior epigastric artery perforator flap. A greater understanding of the procedure's impact on the perfusion of the abdominal skin can be valuable in predicting areas susceptible to necrosis.

Methods: Microcirculatory changes were monitored in the abdominal skin of 20 consecutive patients undergoing breast reconstruction with a deep inferior epigastric artery perforator flap. Quantitative mapping was performed with laser Doppler perfusion imaging at seven set intervals. Measurements were taken and recorded within four standardized zones covering the skin between the xiphoid process and the upper incisional boundary of the flap (zone 1-4; cranial to caudal).

Study Timeline

• Study Start: 2008-01
• Primary Completion: 2009-09
• Study Completion: 2015-03
• Study First Submitted: 2015-05-11
• Status Verified: 2015-06
• Study First Submitted QC: 2015-06-22
• Last Update Submitted: 2015-06-22
• Study First Posted: 2015-06-25
• Last Update Posted: 2015-06-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 20

Inclusion Criteria

• Secondary, unilateral breast reconstruction with a DIEAP
• All smokers stopped smoking 4 weeks prior to surgery

Exclusion Criteria

• Metastatic disease
• Bilateral breast reconstruction

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Laser Doppler Perfusion Imaging	Laser Doppler perfusion imaging	20 consequetive cases undergoing breast reconstruction with Deep inferior epigastric artery perforator flap who had evaluation of the microcirculation of the abdominal skin with laser Doppler perfusion imaging

Primary Outcome Measures

Name	Time	Method
Perfusion of the abdominal zones measured in mean perfusion units	Postoperative day 7 (POD7)

Trial Locations

Locations (1)

Department of Plastic and Reconstructive Surgery; 🇳🇴 Oslo, Norway