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临床试验/NCT02481284
NCT02481284已完成不适用

Microcirculatory Evaluation of the Abdominal Skin in Breast Reconstruction With Deep Inferior Epigastric Artery Perforator Flap

Oslo University Hospital1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2008年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
20
试验地点
1
主要终点
Perfusion of the abdominal zones measured in mean perfusion units

研究概览

简要总结

The purpose of this study was to perform a quantitative perfusion study of the undermined abdominal skin in deep inferior epigastric artery perforator flap breast reconstruction patients in order to obtain more knowledge on perfusion dynamics. Laser Doppler perfusion imaging (LDPI) was used to evaluate this.

Microcirculatory changes were monitored in the abdominal skin of 20 consecutive patients. Measurements were taken and recorded within four standardized zones covering the skin between the xiphoid process and the upper incisional boundary of the flap (zone 1-4; cranial to caudal).

详细描述

Background: No studies have assessed the perfusion of the undermined abdominal skin in breast reconstruction with deep inferior epigastric artery perforator flap. A greater understanding of the procedure's impact on the perfusion of the abdominal skin can be valuable in predicting areas susceptible to necrosis.

Methods: Microcirculatory changes were monitored in the abdominal skin of 20 consecutive patients undergoing breast reconstruction with a deep inferior epigastric artery perforator flap. Quantitative mapping was performed with laser Doppler perfusion imaging at seven set intervals. Measurements were taken and recorded within four standardized zones covering the skin between the xiphoid process and the upper incisional boundary of the flap (zone 1-4; cranial to caudal).

研究设计

研究类型
Observational
时间视角
Prospective

入排标准

性别
Female
接受健康志愿者

入选标准

  • Secondary, unilateral breast reconstruction with a DIEAP
  • All smokers stopped smoking 4 weeks prior to surgery

排除标准

  • Metastatic disease
  • Bilateral breast reconstruction

结局指标

主要结局

Perfusion of the abdominal zones measured in mean perfusion units

时间窗: Postoperative day 7 (POD7)

次要结局

未报告次要终点

研究者

发起方
Oslo University Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Kim Alexander Tønseth

Head of Department

Oslo University Hospital

研究点 (1)

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