A study to check the efficacy and safety of injection of local anesthetic besides the spine (known as paravertebral block)to reduce post-surgery pain in lung resection surgeries.
Not Applicable
- Conditions
- Health Condition 1: C30-C39- Malignant neoplasms of respiratory and intrathoracic organsHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2024/04/065006
- Lead Sponsor
- Tata Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients aged 18 to 80 years undergoing minimally invasive uniportal lung resection surgeries at TMH
Exclusion Criteria
1. Patient’s refusal.
2. Infection at the site of needle insertion.
3. Previous allergic reactions to local anaesthetic (levobupivacaine) and/or paracetamol and/or diclofenac and/or fentanyl.
4. Contraindications to receive paracetamol (liver enzymes more than 5 times the normal values, Child-Pugh B or C) and diclofenac (serum creatinine more than 1.5 mg percent, single-kidney status, blood loss during the surgery more than 1.5 litres, history of aspirin-induced bronchial asthma)
4. Pregnant Women.
5. Multi-port / Robotic minimally invasive surgery
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Time to receive the first rescue analgesic following the minimally invasive uni-portal lung resection surgeryTimepoint: Until 24 hours
- Secondary Outcome Measures
Name Time Method 1.NRS- at rest, NRS- on maximal spirometry effort at 0-4 hours, 8-12 hours, and 24 hours after reaching the recovery room in the postoperative period. <br/ ><br>2.Worst pain score in 24 hours following the surgery. <br/ ><br>3.Maximal spirometry effort (average of three attempts) at 0-4 hours, 8-12 hours, and 24 hours following the minimally invasive uni-portal lung resection surgery. <br/ ><br>4.The total dose of opioids in terms of ‘morphine equivalent’ (including intraoperative dose) received in the first 24 hours following the minimally invasive uni-portal lung resection surgery. <br/ ><br>Timepoint: Until 24 hours