Ridge Splitting With Simultaneous Implant Placement Using i-PRF

Not Applicable

Completed

• Conditions: i-PRF; Ridge Splitting; Dental Implant
• Interventions: Procedure: Immediate implant placement and alveolar ridge splitting with GBR and i-PRF; Procedure: Immediate implant placement and alveolar ridge splitting with GBR

• Registration Number: NCT05010785
• Lead Sponsor: Kafrelsheikh University

Brief Summary

Sohn introduced the concept of sticky bone in which i-PRF is mixed with the granules of bone graft, leading to fabrication of growth factors-enriched bone graft matrix using autologous fibrin glue. This minimizes bone loss and accelerates tissue healing during healing period. The present study was conducted to evaluate the clinical and radiographic outcomes following the application of the alveolar ridge splitting in combination with the use of guided bone regeneration (GBR) with or without i-PRF (sticky bone), associated with immediate implant placement in patients with horizontally atrophic jaw bones.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-08-01
• Study First Submitted QC: 2021-08-15
• Study First Posted: 2021-08-18
• Study Start: 2021-08-20
• Primary Completion: 2022-11-03
• Study Completion: 2022-11-15
• Status Verified: 2023-12
• Last Update Submitted: 2023-12-19
• Last Update Posted: 2023-12-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

• good general health at the time of surgery.
• at least 3 months of healing after tooth extraction.
• horizontally compromised alveolar ridges at least 10 mm high and 3 mm wide.

Exclusion Criteria

• a vertical bone defect in the edentulous ridge.
• thick cortex in the labial/buccal with less cancellous bone inside
• obvious undercut on the labial/buccal side.
• uncontrolled periodontal conditions or other oral disorders.
• history of radiotherapy in the head and neck region.
• uncontrolled diabetes mellitus or other systematic disorders.
• smokers.
• Pregnancy.
• non-compliant patients.
• allergic reaction to the medications used

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
alveolar ridge splitting with GBR and i-PRF	Immediate implant placement and alveolar ridge splitting with GBR and i-PRF	alveolar ridge splitting in combination with the use of GBR with i-PRF (sticky bone) with immediate implant placement
alveolar ridge splitting with GBR	Immediate implant placement and alveolar ridge splitting with GBR	alveolar ridge splitting in combination with the use of GBR without i-PRF (sticky bone) with immediate implant placement

Primary Outcome Measures

Name	Time	Method
Measurements of the amount of bone formation in millimeters around immediately placed dental implants	9 months	Measurements of the amount of bone formation in millimeters using GBR with or without the combined effect of i-PRF in the ridge splitting following immediate implant placement.

Trial Locations

Locations (1)

Faculty of Dentistry, Kafrelsheikh University; 🇪🇬 Kafr Ash Shaykh, Egypt