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Clinical Trials/NCT05107401
NCT05107401
Completed
Not Applicable

Reducing HIV Stigma to Increase HIV Testing Among Adolescents and Young Adults in Kazakhstan Using a Crowdsourcing Approach

Columbia University1 site in 1 country216 target enrollmentJanuary 24, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stigma, Social
Sponsor
Columbia University
Enrollment
216
Locations
1
Primary Endpoint
Mean Score Change in Total HIV Stigma Scale
Status
Completed
Last Updated
last year

Overview

Brief Summary

This project will assess whether a digital crowdsourced intervention can reduce HIV stigma and promote HIV self-testing among adolescents and young adults (AYA). NIH has emphasized the need for research on interventions to reduce HIV-associated stigma and its impact on the prevention and treatment of HIV/AIDS, particularly in low and middle income countries (LMICs). The proposed study has the highest public health significance: it uses a community-based participatory approach to engage local AYA to develop a digital crowdsourced HIV stigma reduction and self-testing intervention to reduce HIV stigma and increase HIV testing.

Study Aim 1: To develop a crowdsourced digital HIV stigma reduction and self-testing intervention targeting AYA in Kazakhstan. Using a community-based participatory approach that engages local adolescents and young adults (AYA) and youth organizations, we will launch a national crowdsourcing contest in which AYA will design multimedia content to reduce HIV stigma in order to promote HIV testing among peers.

Study Aim 2: To pilot test this crowdsourced HIV stigma reduction and self-testing intervention in a preliminary efficacy trial. We will assess the intervention's feasibility and acceptability and obtain preliminary estimates of its effects on decreasing HIV stigma (primary outcome) and increasing HIV testing (secondary outcome) among AYA in Kazakhstan who received the intervention compared to individuals who did not. Participants (n=168) will be randomized 1:1 to: 1) receive the winning multimedia crowdsourced HIV stigma reduction content and a link for HIV self-testing, or 2) receive standard Kazakhstan Ministry of Health HIV informational materials and a link for HIV self-testing.

Detailed Description

This project will assess whether a digital crowdsourced intervention can reduce HIV stigma and promote HIV self-testing among adolescents and young adults (AYA). Globally AYA are at increased risk for HIV acquisition. In Eastern Europe and Central Asia (EECA), new HIV infections among 15-24 year old AYA are expected to increase 28% by 2030. In Kazakhstan, one in four HIV infections occur among AYA. Despite the growing HIV burden among AYA in Kazakhstan, this population has some of the lowest HIV testing rates in the country, largely due to stigma. Yet few efforts in Kazakhstan address HIV stigma and the role it plays as a barrier to HIV testing. Digital technologies and crowdsourcing campaigns (i.e., engaging groups of AYA online to address public health challenges and share solutions) are scalable, cost-effective tools that can increase HIV testing services and reduce HIV stigma in low and middle income countries (LMICs) and other resource- constrained settings. Crowdsourcing may be particularly successful among AYA, given their high levels of social media use and technological literacy. Complementing the crowdsourcing approach, mailing HIV rapid test kits can enable AYA to avoid the stigma associated with attending the AIDS Center and overcome transportation barriers.

Registry
clinicaltrials.gov
Start Date
January 24, 2023
End Date
August 22, 2023
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Alissa Davis

Assistant Professor of Social Work, School of Social Work

Columbia University

Eligibility Criteria

Inclusion Criteria

  • Age 16-24
  • Report previous sex with another individual
  • Reside in Kazakhstan

Exclusion Criteria

  • Not willing to provide consent or not able to understand study procedures

Outcomes

Primary Outcomes

Mean Score Change in Total HIV Stigma Scale

Time Frame: Baseline and 3 months

The scale/questionnaire is comprised of 17 items on a 5-point Likert scale (score range from 17-85). Higher scores indicate higher levels of stigma. Outcome will be assessed in mean score change from baseline to 3 months follow-up.

Secondary Outcomes

  • Mean Change in Perceived HIV Test Stigma(Baseline and 3 months)
  • Mean Change in Perceived HIV Healthcare Stigma Subscale(Baseline and 3 months)
  • Mean Change in Fear & Judgement HIV Stigma Sub-scale(Baseline and 3 months)
  • Mean Change in Perceived Community HIV Stigma Subscale(Baseline and 3 months)
  • Uptake of HIV Self-test(After baseline and by the 3 month follow-up period)

Study Sites (1)

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