Fetal Pulmonary Artery Acceleration to Ejection Time Ratio (PATET) in the Prediction of Subsequent Development of Respiratory Distress Syndrome (RDS)

Completed

• Conditions: RDS
• Interventions: Device: ultrasound examination

• Registration Number: NCT03008200
• Lead Sponsor: Kayseri Education and Research Hospital

Brief Summary

Fetal PATET ratio evaluation to predict neonatal RDS

Detailed Description

115 patients were enrolled in this study.Population was recruited from singleton pregnancies beyond 27 weeks of gestation.All participants underwent a ultrasound examination to measure fetal pulmonary artery acceleration to ejection time ratio (PATET) by a single experienced clinician. After the delivery respiratory distress diagnosis made by a pediatrician who were blinded the doppler waveform measurements.Following the diagnosis, neonates divided into 2 groups as RDS (+) and RDS (-). In addition of RDS diagnosis, neonatal features like 1st and 5th minute APGAR scores, neonatal intensive care unit (NICU) admission and duration in NICU were also recorded. Afterwards all parameters were statistically analyzed if there is any significant differences between those two groups.

Study Timeline

• Study Start: 2015-12
• Primary Completion: 2016-09
• Study Completion: 2016-09
• Status Verified: 2016-12
• Study First Submitted: 2016-12-20
• Study First Submitted QC: 2016-12-28
• Last Update Submitted: 2016-12-31
• Study First Posted: 2017-01-02
• Last Update Posted: 2017-01-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 115

Inclusion Criteria

• pregnant women within the 27 weeks of gestation and beyond

Exclusion Criteria

• patients who did not give birth within 3 days after the ultrasonographic doppler examination
• fetuses with Any congenital abnormalities
• amniotic fluid abnormalities
• any chronic maternal diseases or pregnancy complications such as;gestational diabetes mellitus,preeclampsia

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
RDS -	ultrasound examination	postpartum RDS undeveloped group
RDS +	ultrasound examination	postpartum RDS developed group

Primary Outcome Measures

Name	Time	Method
Measurement of fetal pulmonary acceleration time to ejection time ratio via ultrasonography in the 115 pregnant women between 27 to 37 weeks of gestation for prediction of respiratory distress syndrome	Ten months	The aim of this study is to obtain the effectiveness of fetal pulmonary artery acceleration time to ejection time ratio in fetal lung maturity evaluation