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临床试验/CTRI/2024/12/077864
CTRI/2024/12/077864尚未招募3 期

Efficacy of vangadi yoga and kapikacchu churna in the management of oligozoospermia A randomized controlled clinical trial

Dr Rohan Mohandas1 个研究点 分布在 1 个国家目标入组 56 人开始时间: 2025年1月1日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
56
试验地点
1
主要终点
Changes in Sperm Count

研究概览

简要总结

Infertility is defined as: “A failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse Of all the sexually active couples, 12% to 15% are infertile, of which a male component can be identified 50% of the time either individually or along with the female component.Male infertility refers to a male’s inability to result pregnancy in a fertile female. “Male factor” infertility is seen as an alteration in sperm concentration and/or motility and/or morphology in at least one sample of two sperm analyses, collected 1 and 4 weeks apart. Males with sperm parameters below the WHO normal values are considered to have male factor infertility. The most significant of these are low sperm concentration (oligozoospermia) poor sperm motility (asthenozoospermia), and abnormal sperm morphology (teratozoospermia) Male infertility is an alarming global health issue that has not been researched or studied to truly understand its magnitude and prevalence. There is still a great need for further research into underlying etiology and treatment of male infertility.Ayurveda explains Vajikarana Chikitsa for the problems related to fertility and sexual functions.

Vangadi yoga is One such formulation is mentioned in Rasatarangini, in the chapter of Vanga bhasmawhere in it is said that:vanga bhasma taken with the Shalmali and Abrakha Bhasma is Shukra Janana param i.e it is most potent in increasing the sperm count

The present study is randomized controlled clinical trial with a sample size of 56 , 28 in each group one group will recieve vangadi yoga and other group will recieve control drug kapikacchu churna for duration of 45 day the participants will be assessed on baseline and 45th day by semen parameters

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
20.00 Year(s) 至 50.00 Year(s)(—)
性别
Male

入选标准

  • Diagnosed cases of Oligozoospermia.
  • Subjects within the age group of 20 to 50 years.
  • Subjects either married or unmarried.
  • Subjects indicated for Koshta shodhana (Sadyo virechana ) Subjects who are ready to voluntarily sign the informed consent form.

排除标准

  • Subjects with uncontrolled /untreated metabolic disorders, long-standing infections, chronic liver & renal disease or any psychiatric illness.
  • Accessory sex gland infection , STD’s, testicular maldescent , Hydrocele , varicocele more then grade II, neoplasms, Subjects with recent history of Orchitis, Trauma and Acute febrile illness, Diagnosed cases of Azoospermia.
  • Subjects exposed to environmental chemicals, thermal exposure, X-ray radiation and chemotherapeutic agents will be taken into consideration.
  • Subjects who have undergone Vasectomy and under long standing medications (Alpha blockers,SSRI’s, Steroids, androgens) be taken into consideration.

结局指标

主要结局

Changes in Sperm Count

时间窗: Baseline and 45th day

次要结局

  • Changes in the Sperm motility(Sperm Morphology)

研究者

发起方
Dr Rohan Mohandas
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Rohan Mohandas

KAHERS Shri BMK Ayurveda Mahavidyalaya Shahapur Belagavi

研究点 (1)

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