Comparison of Fractional Flow Reserve Versus Instant Wave-Free Ratio for Assessment of Coronary Artery Stenosis Severity in Routine Practice
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 5
- 主要终点
- Comparison of Fractional Flow Reserve vs. instant Wave-Free Ratio for assessment of coronary artery stenosis severity in routine practice
研究概览
简要总结
Comparison of Fractional Flow Reserve versus instant Wave-Free Ratio for assessment of coronary artery stenosis severity in routine practice
- To compare FFR to iFR in arbitrary consecutive patients referred for percutaneous coronary intervention (PCI).
- To investigate the influence of hyperemia on iFR.
- To test reproducibility of iFR and FFR.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all consecutive patients undergoing FFR assessment for standard clinical indications.
排除标准
- •prior CABG
- •extremely tortuous, calcified lesions
- •coronary artery occlusion
- •acute MI within 5 days
结局指标
主要结局
Comparison of Fractional Flow Reserve vs. instant Wave-Free Ratio for assessment of coronary artery stenosis severity in routine practice
时间窗: 30 days
In this prospective, multicenter, international investigation, all consecutive patients in 5 centers, referred for PCI will be included. FFR will be submitted for one vessel in each patient - this will be the first vessel in which the FFR is performed. Measurements will be performed in duplicate. iFR will be calculated for all lesions for which an FFR measurement is submitted. In addition, iFR and FFR will be compared retrospectively in 1000 patients who had FFR measurements in the recent past
次要结局
- iFR at rest vs iFr during hyperemia(30 days)
- Repeatability of iFr and FFR(30 days)
研究者
Prof. Keith G. Oldroyd
Consultant Cardiologist
NHS National Waiting Times Centre Board