Evaluation of Conventional Collagen Crosslinking in Young Keratoconus.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Vasan Eye Care Hospital
- Enrollment
- 21
- Locations
- 2
- Primary Endpoint
- Change in Keratometric indices
Study Overview
Brief Summary
Keratoconus is a chronic progressive non - inflammatory disorder characterised by progressive steepening and thinning of cornea and high myopic astigmatism, accounting for poor visual acuity in such individuals. Keratoconus seems to be more advanced on presentation, in young patients.
The investigators intend to evaluate the effectiveness of conventional collagen cross linking in young patients diagnosed with keratoconus.
Detailed Description
Keratoconus is progressive ectatic corneal disorder characterised by progressive corneal thinning, steep corneal curvatures and usually associated with high irregular myopic astigmatism.
The major problems concerning keratoconus in young patients are;
- Rapid rates of progression in young keratoconic corneas as compared to adults.
- Poor biomechanical properties of young corneas.
- Poor quality of vision, which predisposes to a very poor quality of life.
- High rates of complications and failure post keratoplasty in young patients.
The investigators intend to evaluate the effectiveness of conventional collagen crosslinking in young patients with keratoconus with regards to keratometric indices and visual acuity.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 3 Years to 18 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients aged 18 years and below.
- •Patients diagnosed to have keratoconus at presentation and willing for follow - up at regular intervals post treatment.
Exclusion Criteria
- •Any disease causing abnormal topography other than keratoconus.
- •Any ocular condition predisposing towards poor vision (retinal , lens problems)
Outcomes
Primary Outcomes
Change in Keratometric indices
Time Frame: 1 months
The keratometric readings in the steepest and flattest meridians, along with the average K readings were compared pre and post treatment using conventional collagen cross linking technique at 1 month post cross linking.
Secondary Outcomes
- Improvement in vision(12 months)
Investigators
Dr.ANAND PARTHASARATHY, Dr. Ramesh Hariharan
Dr. Anand Parthasarathy
Vasan Eye Care Hospital