Brain Tumor Surgery and Postoperative Delirium

Not Applicable

Not yet recruiting

• Conditions: Brain Tumor
• Interventions: Drug: Dexmedetomidine; Drug: Normal Saline

• Registration Number: NCT06863064
• Lead Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital

Brief Summary

1. To explore whether the combined administration of dexmedetomidine during and after surgery in patients undergoing brain tumor resection is an effective and safe modality to prevent postoperative delirium and improve sleep quality than giving it alone after surgery.

2. To explore whether intraoperative and postoperative administration of dexmedetomidine to patients undergoing brain tumor surgery can reduce postoperative acute pain and prevent chronic pain.

3. To explore whether intraoperative and postoperative administration of dexmedetomidine to patients undergoing brain tumor surgery can provide stable anesthesia depth, hemodynamics and reduce the dose of anesthetics, thereby accelerating patient recovery.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-02-04
• Status Verified: 2025-03
• Study Start: 2025-03-01
• Study First Submitted QC: 2025-03-04
• Last Update Submitted: 2025-03-04
• Study First Posted: 2025-03-07
• Last Update Posted: 2025-03-07
• Primary Completion: 2027-12-31
• Study Completion: 2027-12-31

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

• at least 18 years old and less than 80 years old
• receive brain tumor surgery with ASA II~III.

Exclusion Criteria

• under the age of 18 or over 80
• consciousness unclear
• those who have not signed a consent form
• those with high anesthesia risk ASA IV or higher

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Participant Group	Dexmedetomidine	brain tumor postoperative
Participant Group	Normal Saline	brain tumor postoperative

Primary Outcome Measures

Name	Time	Method
Assessment and Documentation of Delirium	1 to 3 days post-surgery.	Richards Campbell Sleep Questionnaire (RCSQ) ,The score ranges from 0 to 100, with 100 being the best.

Trial Locations

Locations (1)

Kaohsiung Medical University Chung-Ho Memorial Hospital; 🇨🇳 Kaohsiung, Taiwan