Effect of Inferior Alveolar and Gow-Gates Nerve Block Techniques for Symptomatic Mandibular Molars

Phase 3

Completed

• Conditions: Symptomatic Irreversible Pulpitis
• Interventions: Procedure: GGNB injections; Procedure: IANB injections; Procedure: GGNB + IANB injections

• Registration Number: NCT03117491
• Lead Sponsor: Isfahan University of Medical Sciences

Brief Summary

Introduction: to evaluate the efficacy of inferior alveolar nerve block (IANB), Gow-Gates nerve block (GGNB), and their combination in patients with irreversible pulpitis. Methods: One hundred fifty subjects with irreversible pulpitis of a mandibular molar were selected. subjects randomly received two IANB injections or two GGNB injections or their combination of 1.8 mL 2% lidocaine with 1:100,000 epinephrine. Success was specified as no or mild pain on the basis of Heft-Parker visual analogue scale recordings up on the access cavity preparation or initial instrumentation. Data were analyzed by Kruskal-Wallis, and ANOVA tests.

Detailed Description

Introduction: to evaluate the efficacy of inferior alveolar nerve block (IANB), Gow-Gates nerve block (GGNB), and their combination in patients with irreversible pulpitis. Methods: One hundred fifty subjects with irreversible pulpitis of a mandibular molar were selected. subjects randomly received two IANB injections or two GGNB injections or their combination of 1.8 mL 2% lidocaine with 1:100,000 epinephrine. Success was specified as no or mild pain on the basis of Heft-Parker visual analogue scale recordings up on the access cavity preparation or initial instrumentation. Data were analyzed by Kruskal-Wallis, and ANOVA tests.

Study Timeline

• Study Start: 2015-12-01
• Primary Completion: 2016-11-01
• Study Completion: 2016-12-01
• Status Verified: 2017-04
• Study First Submitted: 2017-04-03
• Study First Submitted QC: 2017-04-12
• Study First Posted: 2017-04-18
• Last Update Submitted: 2017-05-04
• Last Update Posted: 2017-05-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• vital mandibular molar tooth
• diagnosis of symptomatic irreversible pulpitis

Exclusion Criteria

• younger than 18 years old
• history of significant medical conditions
• allergies to local anesthetics or sulfites
• pregnancy
• taking any medications that might influence anesthetic assessment
• active sites of pathosis in area of injection
• inability to give informed consent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
GGNB injection technique	GGNB injections	In GGNB group, every patient received two1.8-mL cartridges of 2% lidocaine with 1:80,000 epinephrine using the GGNB technique
IANB injection technique	IANB injections	In IANB group, every patient received two 1.8-mL cartridges of 2% lidocaine with 1:80,000 epinephrine using the IANB technique
GGNB + IANB injection technique	GGNB + IANB injections	In IANB + GGNB group, every patient received one 1.8-mL cartridges of 2% lidocaine with 1:80,000 epinephrine using the IANB technique and one 1.8-mL cartridges of 2% lidocaine with 1:80,000 epinephrine using the GGNB technique

Primary Outcome Measures

Name	Time	Method
the success rate of GGNB + IANB local anesthesia techniques based on Heft-Parker visual analog scale	at time of access cavity preparation
the success rate of IANB local anesthesia technique based on Heft-Parker visual analog scale	at time of access cavity preparation
the success rate of GGNB local anesthesia technique based on Heft-Parker visual analog scale	at time of access cavity preparation

Secondary Outcome Measures

Name	Time	Method
initial pain based on Heft-Parker visual analog scale	before treatment

Trial Locations

Locations (1)

Isfahan University of Medical Sciences; 🇮🇷 Isfahan, Iran, Islamic Republic of