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ASSESSMENT OF DEVELOPMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA

Not Applicable
Not yet recruiting
Conditions
Health Condition 1: G473- Sleep apnea
Registration Number
CTRI/2021/06/034461
Lead Sponsor
ALL INDIA INSTITUTE OF MEDICAL SCIENCES RISHIKESH
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Not Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Age > 18 years.

2. Diagnosis of OSA based on International Classification of Sleep Disorders (ICSD) â?? 3 criteria:

ï?· Diagnosis requires (A+B) or C:

A. The presence of one or more of the following:

1.The patient complains of sleepiness, nonrestorative sleep, fatigue, or insomnia symptoms.

2.The patient wakes with breath holding, gasping, or choking.

3.The bed partner or other observer reports habitual snoring, breathing interruptions, or both during the patientâ??s sleep.

4.The patient has been diagnosed with hypertension, a mood disorder, cognitive dysfunction, coronary artery disease, stroke, congestive heart failure, atrial fibrillation, or type 2 diabetes mellitus.

B. Polysomnography (PSG) or OCST demonstrates:

Five or more predominantly obstructive respiratory events (obstructive and mixed apneas, hypopneas, or respiratory effort related arousals [RERAs]) per hour of sleep during a PSG or per hour of monitoring (OCST).

C. PSG or OCST demonstrates:

Fifteen or more predominantly obstructive respiratory events (apneas, hypopneas, or RERAs) per hour of sleep during a PSG or per hour of monitoring (OCST).

3. Non-alcoholic individuals or individuals who consume less than 20 g of alcohol per day. History will be confirmed by two family members.

Exclusion Criteria

1.Age <18 years

2.Causes of Chronic liver disease other than NAFLD

3.Patients with secondary causes of NAFLD such as drugs, jejunoileal bypass or extensive small bowel resection or total parenteral nutrition.

4. Patients who do not give consent

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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