Early prediction of menopausal status in pre/perimenopausal women with early breast cancer after (neo) adjuvant chemotherapy in order to optimize adjuvant endocrine therapy
Recruiting
- Conditions
- primary hormone receptor positive breast cancer
- Registration Number
- NL-OMON28140
- Lead Sponsor
- none
- Brief Summary
not yet
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
•Primary hormone-sensitive (ER >10% positive and/or PgR >10% positive) breast cancer, independent of Her2- receptor status, curatively locally treated
Exclusion Criteria
•Bilateral oophorectomy
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method recovery of ovarian function is defined as resumption of menstrual cyclicity (at least more than 1 episode of vaginal bleeding, not caused by vaginal atrophy) and/or levels of estradiol and FSH in the postmenopausal range (according to the local laboratory values; in general >110 pmol/l and <20 pmol/l, respectively), being reconfirmed at least once.
- Secondary Outcome Measures
Name Time Method