Post Operative Delirium Study
- Conditions
- Delirium
- Registration Number
- NCT04635774
- Lead Sponsor
- University of Kansas Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- All
- Target Recruitment
- 0
Inclusion Criteria:<br><br> - All patients (>65 years of age) undergoing elective surgery using vapor anesthesia<br> displaying post-operative delirium as defined by a CAM evaluation within time to<br> PACU discharge post-surgery are eligible.<br><br> - Those patients 65 and older undergoing surgery using vapor anesthesia, who are<br> consented but do not exhibit delirium and are not part of the study are still<br> considered recruited subjects, but are not in the active study.<br><br>Exclusion Criteria:<br><br> - Patients with a history of severe dementia, anoxic brain injury, or neuromuscular<br> disorders<br><br> - Non-English-speaking patients<br><br> - Planned use of drugs that effect plasma glucose concentration during the first four<br> hours of surgery<br><br> - thiazolidinediones<br><br> - hormones which may affect plasma glucose or insulin<br><br> - contraceptive, diphenylhydantoin<br><br> - patients with allergy to insulin<br><br> - acromegaly<br><br> - Cushing's syndrome<br><br> - hyperthyroidism and pheochromocytoma<br><br> - renal impairment<br><br> - pregnant and lactating women<br><br> - base line blood glucose < 3.9 mmol/L
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Efficacy of intranasal insulin in resolving post-operative delirium;Efficacy of intranasal insulin in resolving post-operative delirium;Efficacy of intranasal insulin in resolving post-operative delirium;Efficacy of intranasal insulin in resolving post-operative delirium
- Secondary Outcome Measures
Name Time Method Length of stay in the post-anesthesia care unit (PACU)