TCTR20220814002已完成4 期
Additional nefopam reduces postoperative pain after primary total knee arthroplasty: a randomized controlled trial
Phyathai 3 Hospital0 个研究点目标入组 80 人开始时间: 2022年8月14日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 80
研究概览
简要总结
Patients in nefopam group had higher pain score and higher amount of morphine consumption at 24 hours postoperative as well as difference in overall pain. Neither the amount of morphine consumption at other time points nor the knee range of motion differed between two groups.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 50 Years 至 85 Years（—）
- 性别
- All
入选标准
- •1 Primary OA knee
- •2 Age between 50 to 85 years
- •3 Fully comprehension of Thai language
排除标准
- •1 Previous ipsilateral knee surgery
- •2 Contraindication to drugs used in the study (nefopam, ketorolac, parecoxib, paracetamol, tranexamic acid)
- •3 Chronic kidney disease which GFR <50 ml/min
- •4 Arrhythmic heart disease
- •5 Psychiatric disorder receiving serotonin or tramadol
- •6 Intraoperative fracture or ligamentous injury
研究者
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