Effectiveness of oral vitamin D3 supplementation on clinical parameters and serum TNF alpha levels in subjects with minor recurrent aphthous stomatitis having hypovitaminosis D - A randomized controlled trial - NI

Government Dental College and Research Institute Bangalore0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年4月29日

试验速览

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•Subjects aged 18 to 60 years of both genders, diagnosed according to Major and Minor Diagnostic criteria of Recurrent Aphthous Stomatitis as given by Natah et al in 2004. All four major and one minor criterion are to be fulfilled for diagnosis of RAS.
•Subjects with Serum Vitamin D less than 30 ng/ml who voluntarily consented to be a part of the study

•Subjects having received any systemic medication for Recurrent Aphthous Stomatitis(RAS) in the last three months.
•Subjects with history of use of vitamin D supplements in a general multivitamin, along with calcium supplements or antioxidants or have already received Vitamin D3 as a treatment for another underlying disease at the time of the start of our study.
•Subjects who were taking any drug affecting TNF-alpha levels or vitamin D metabolism in past six months.
•Subjects with history of known allergy to vitamin D supplements
•Subjects with any systemic disease affecting vitamin D metabolism.
•Subjects with any oral ulcers other than RAS minor.
•Habit of smoking
•Pregnant and lactating females

发起方

Government Dental College and Research Institute Bangalore