A multidisciplinary research capability improvement project in Chinese medicine based on the research field of key research office--Research on machine learning to mine the medication patterns of Chinese medicine

Not Applicable

• Conditions: Coronary heart disease

• Registration Number: ITMCTR2023000046
• Lead Sponsor: The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 16 October 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Meet the diagnostic criteria for coronary heart disease
2. Record at least one hospitalization
3. Length of hospital stay is greater than or equal to 7 days
4. Use of traditional Chinese medicine in hospitalization

Exclusion Criteria

1. Patients with valvular heart disease, various types of cardiomyopathy, malignant arrhythmia, and NYHA functional classification III-IV heart failure;
2. Patients diagnosed with severe brain tumors or traumatic brain diseases;
3. Patients with acute cerebrovascular disease that occurred in the past 2 weeks, severe pulmonary dysfunction (PaO2 <60mmHg), severe primary diseases of the endocrine and hematopoietic system (aplastic anemia, leukemia, leukopenia and neutropenia, malignant lymphoma Primary immune thrombocytopenia (idiopathic thrombocytopenic purpura), thrombotic thrombocytopenic purpura, primary polycythemia vera, bone marrow abnormal proliferation syndrome, primary myelofibrosis, multiple myeloma, pituitary tumor, diabetes, prolactinoma, thyroid crisis, primary adrenal insufficiency (Addison's disease), Cushing's syndrome, insulinoma), moderate to severe hepatic dysfunction (transaminase levels exceeding the upper limit of normal 3 times) or renal dysfunction (eGFR less than 60/min/1.73m2), and high creatinine levels exceeding the normal value;
4. History of infection, fever, trauma, burns, or surgery in the past month;
5. Patients with poor compliance and difficult to follow-up;
6. Patients with severe visual or auditory impairment, serious cognitive communication impairment, and a history of mental illness;
7. Patients with untreated or uncontrolled hypertension (BP=180/100mmHg).

Study & Design

• Study Type: Observational study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
CM medication pattern (TCM combined with western medication or western medication only) to intervene in CHD;Clinical symptoms;Whether there is a coronary stent;Whether or not coronary angiography has been done;Lipid levels;Whether heart bypass graft has been done;The four qi and five flavors of Chinese herbs attributed to the meridian;