EUCTR2006-005451-15-IT进行中（未招募）不适用
GR006 A phase II study of NGR-hTNF administered as single agent every 3 weeks in patients affected by colorectal cancer CRC , previously treated with fluoropyrimidine, oxaliplatin and irinotecan based regimens. - NGR006
MOLMED0 个研究点目标入组 27 人开始时间: 2007年1月24日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 27
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Patients 18 years affected by advanced or metastatic colorectal cancer CRC , previously treated with fluoropyrimidine, oxaliplatin and irinotecan based regimens. Adjuvant chemotherapy following definitive management of the primary lesion is allowed and will not be counted as a line of therapy ECOG Performance status 0 1 Patients in progression disease at study entry CT documented Adequate baseline bone marrow, hepatic cardiac and renal functions -absence of any conditions in which hypervoleamia and its consequences Patients must give written informed consent
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •More than three lines of chemotherapy except biological agents Concurrent anticancer therapy Patients may not receive any other investigational agents while on study Clinical signs of CNS involvement Patients with active or uncontrolled systemic disease/infections or with serious illness or medical conditions, which is incompatible with the protocol Known hypersensitivity/allergic reaction to human albumin preparations or to any of the excipients Any psychological, familial, sociological or geographical condition potentially hampering compliance with the study protocol Pregnancy or lactation.
研究者
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GR018: Randomized study based on administration of NGR-hTNF plus an anthracycline versus an anthracycline alone in platinum-resistant ovarian cancerAdvanced or metastatic platinum-resistant ovarian cancer patientsEUCTR2012-005745-20-ITMolMed S.p.A.24