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Clinical Trials/NCT01928108
NCT01928108
Completed
Not Applicable

Do Different Methods of Educating Patients Regarding Fluid Intake Reduce Kidney Stone Risks?

University of North Carolina, Chapel Hill1 site in 1 country10 target enrollmentJuly 2013
ConditionsKidney Stone

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Kidney Stone
Sponsor
University of North Carolina, Chapel Hill
Enrollment
10
Locations
1
Primary Endpoint
24-hour urine volume
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

The purpose of this investigation is to prospectively evaluate the benefit of different methods of educating patients regarding their fluid intake through a readily available daily cellular phone application to improve overall urine output and reduce risk factors for stone recurrence.

Detailed Description

The prevalence of kidney stone disease in the United States is increasing. Recurrence of kidney stone disease has been reported as high as 50% at five years. Urine supersaturation is a predominant factor in the formation of crystallization and stone disease and is dependent on fluid volume. High fluid consumption that dilutes the urine has been shown both in vitro and in clinical studies to reduce the tendency for stone crystallization as well as effectively decrease stone recurrence. As a result, water intake greater than two liters per day is a common initial therapy for prevention of stone disease. However, studies have shown that despite physician counseling most patients are only able to modestly increase their urine volume through fluid intake. This finding may be due to a discrepancy in patient perception of their actual fluid intake and resulting urine volume. The purpose of this investigation is to prospectively evaluate the benefit of different methods of educating patient regarding their fluid intake through a readily available daily cellular phone application to improve overall urine output and reduce risk factors for stone recurrence.

Registry
clinicaltrials.gov
Start Date
July 2013
End Date
March 16, 2017
Last Updated
9 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients ≥ 18 years old
  • Seen in urology or nephrology clinic at UNC with a diagnosis of kidney stone
  • Prior 24-hour urine result with volume less than 2 to 2.5 liters

Exclusion Criteria

  • Patient without cellular phone capable of utilizing Android / Apple application
  • Patient already using some form of monitoring fluid intake / volume
  • Inability to take fluid by mouth
  • Patient with urinary diversion, chronic diarrhea, bowel diversion or other forms of excessive fluid loss
  • Inability to obtain informed consent
  • Non-English speaking

Outcomes

Primary Outcomes

24-hour urine volume

Time Frame: 7-10 days from baseline

Secondary Outcomes

  • Actual 24-hour urine volume vs. patient perceived urine volume(7-10 days from baseline)
  • Ease and interest in monitoring fluid intake based on survey data(7-10 days from baseline)

Study Sites (1)

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