Assessment of postoperative analgesic effect of Bupivacaine and Magnesium sulphate vs Bupivacaine and Dexmedetomidine in ultrasound-guided Transversus abdominis plane block for all laparoscopic surgeries
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To observe the duration of analgesia between the two different study groups
研究概览
简要总结
Patients who are fulfilling inclusion criteria will be randomly allocated to two groups based on computer generated randomisation
Group A Under sterile aseptic precautions TAP block will be given with combination of 0.25% Bupivacaine and 150 mg Magnesium sulphate
Group B Under sterile aseptic precautions TAP block will be given with 20ml on each side combination of 0.25% Bupivacaine and 0.5 mcg/kg Dexmedetomidine
Postoperatively the patients will be monitored for vital parameters and PAIN SCORES (VAS score, NRS score) at 4h, 8h, 12h ,18h and 24 h The time of requirement of first rescue analgesia will be noted and Outcomes will be recorded for interpretation
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 16.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients posted all laparoscopic surgeries ASA grade 1 and ASA grade 2 patient who are willing to participate.
排除标准
- •ASA grade 3 and ASA grade 4 Patients who are known case of hypersensitivity to amide group of local anesthetic agents Patients with coagulation disorders patient who are not willing to participate.
结局指标
主要结局
To observe the duration of analgesia between the two different study groups
时间窗: by observing hourly VAS score
次要结局
- To find out the time of first rescue analgesia(To find out the Pain score at 4hr 8hr 12hr 18hr and 24hr postoperatively)
研究者
Vinisha Sridhar
Sree Balaji medical college and hospital