Optimizing an mHealth intervention to improve uptake and adherence of the HIV pre-exposure prophylaxis (PrEP) among Thai young transgender wome

Phase 1

• Conditions: HIV pre-exposure prophylaxis (PrEP) among Thai young transgender women; PrEP among Thai young TGW

• Registration Number: TCTR20210914003
• Lead Sponsor: IH

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-09-14
• Study Completion: 2023-12-20
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: Male
• Target Recruitment: 200

Inclusion Criteria

Inclusion:
1.Thai Nationality 2.Age 18-29 years old 3.Male sex at birth 4.Self-identifies as woman or TGW or culturally identifies with the female spectrum 5.Laboratory confirmed HIV negative status 6.Self-reported recent history of condomless sex 7.Either not started PrEP (Group 1: PrEP naive) or currently on PrEP but not adherent (taking 3 pills/week) in the past month (Group 2: PrEP users)

Exclusion Criteria

Exclusion:
1.A serious cognitive or psychiatric problem compromising ability to provide informed consent
2.Active suicidal ideation or major mental illness (e.g., untreated psychosis or mania) at the time of interview (patients will be referred for treatment) 3.Laboratory or clinical findings that would preclude PrEP initiation (e.g., decreased creatinine clearance) 4.Currently enrolled in another HIV intervention study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Phase IA (R21 Phase) ADAPT-ITT First phase of ADAPT-ITT model. We propose to utilize a qualitative approach to explore PrEP uptake and usage in young TGW. conduct interviews 40 HIV-neg TGW, 10 providers, community health workers.

Secondary Outcome Measures

Name	Time	Method
/A N/A N/A