Modulation of Visually Evoked Potentials by an Antidepressant

Not Applicable

Completed

• Conditions: Depression

• Registration Number: NCT00263133
• Lead Sponsor: University Hospital Freiburg

Brief Summary

12 normal healthy controls will be treated with 50 mg sertraline once daily for three weeks. Early amplitudes of visually evoked potentials will be examined at day 0, 10 and 21 and statistically compared. This study aims to examine a putative modulation of synaptic transmission and plasticity by an antidepressant and is part of a series of studies in healthy individuals and depressed patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-12
• Study First Submitted: 2005-12-06
• Study First Submitted QC: 2005-12-06
• Study First Posted: 2005-12-07
• Study Completion: 2006-01
• Status Verified: 2007-05
• Last Update Submitted: 2007-06-01
• Last Update Posted: 2007-06-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• healthy individuals 18-65 years

Exclusion Criteria

• history of affective oder other psyhiatric disorder
• severe medical condition
• pregnancy or ineffective contraception
• active illicit drug use

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Amplitudes and latencies of early visually evoked potentials.

Trial Locations

Locations (1)

Dept. of Psychiatry, University of Freiburg; 🇩🇪 Freiburg, Germany