Narrative Exposure Therapy in Women With Borderline Personality Disorder and Posttraumatic Stress Disorder
- Conditions
- Stress Disorders, Post-TraumaticBorderline Personality Disorder
- Registration Number
- NCT02517723
- Lead Sponsor
- Evangelisches Krankenhaus Bielefeld gGmbH
- Brief Summary
Narrative Exposure Therapy (NET) is an evidence-based trauma-focussed treatment, suitable for survivors of prolonged and repeated exposure to traumatic stress and childhood adversity. Patients with Borderline Personality Disorder (BPD) often suffer from a comorbid Posttraumatic Stress Disorder (PTSD) caused by multiple traumatic events. Therapeutic aims are the reduction of PTSD-Symptoms in these patients via activation of associative neural networks related to traumatic experiences and habituation of fear and the placement of traumatic experiences in a reconstructed, detailed and consistent autobiography. This practice enables the processing of and coping with painful memories and the construction of clear contingencies of dangerous and safe conditions, generally leading to significant emotional recovery. The investigators assume that using NET the reduction of PTSD symptom severity is greater compared to treatment by Dialectical-Behavioral Therapy (DBT).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 67
- age ≥ 18 years
- DSM-IV-TR diagnoses of BPD and PTSD
- legal competence
- none or stable medication
- illegal drug abstinence for at least the last 6 months
- capacity to consent and contract
- other severe mental disorders (e.g., bipolar disorder, acute psychosis)
- simultaneous consumption of drugs
- simultaneous participation in other treatment-studies
- pregnancy or breastfeeding
- lack of capability to negotiate a no-suicide agreement
- suicide attempt or attempts during the 8 weeks prior to start of treatment
- perpetrator-contact
- Body Mass Index (BMI) < 16
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- FACTORIAL
- Primary Outcome Measures
Name Time Method Change from first investigation in Posttraumatic Symptom Severity at 18 months (Clinician-Administered PTSD Scale; CAPS) first investigation (t1), after waiting list (3 months, t2), directly after therapy (3 months, t1), 1 year after therapy (15 months, t3)
- Secondary Outcome Measures
Name Time Method Change from first investigation in Severity of Dissociative Symptoms at 18 months (Fragebogen zu Dissoziativen Symptome ;FDS) first investigation (t1), after waiting list (3 months, t2), directly after therapy (6 months, t3), 1 year after therapy (18 months, t4) Change from first investigation in Borderline Symptome Severity at 18 months(Borderline Symptom Liste; BSL) first investigation (t1), after waiting list (3 months, t2), directly after therapy (6 months, t3), 1 year after therapy (18 months, t4) Change from first investigation in Severity of Depressive Symptoms at 18 months (Becks Depressions Inventar II, BDI-II) first investigation (t1), after waiting list (3 months, t2), directly after therapy (6 months, t3), 1 year after therapy (18 months, t4) Change from first investigation in Quality of Life at 12 months (WHO-Qualitiy of Life; WHOQOL) first investigation (t1), after waiting list (3 months, t2), directly after therapy (6 months, t3), 1 year after therapy (18 months, t4)
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Trial Locations
- Locations (1)
Clinic of Psychiatry, Evangelisches Krankenhaus Bielefeld
🇩🇪Bielefeld, Germany
Clinic of Psychiatry, Evangelisches Krankenhaus Bielefeld🇩🇪Bielefeld, Germany