Evaluation of the Association Between Day and Time of Admission to Critical Care and Acute Hospital Outcome for Unplanned Admissions to Adult, General Critical Care Units in the United Kingdom
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 195,428
- 主要终点
- Acute hospital mortality
研究概览
简要总结
A retrospective analysis of the Case Mix Programme database to evaluate the association between day and time of admission to critical care and acute hospital outcome for unplanned admissions to adult, general critical care units in England, Wales and Northern Ireland.
详细描述
- Objective
To conduct an analysis of the Case Mix Programme database to evaluate the association between day and time of admission to critical care and acute hospital outcome for unplanned admissions to National Health Service adult, general critical care units in England, Wales and Northern Ireland. 2. Exposure
The primary exposure variable will be the day and time of admission to the critical care unit, dividing the week into 14 time periods: Monday 08:00-17:59; Monday 18:00-Tuesday 07:59; Tuesday 08:00-17:59, etc.
For summary tables, these will be collapsed into the following categories:
- Weekday daytime: Monday-Friday 08:00-17:59
- Weekend daytime: Saturday-Sunday 08:00-17:59
- Weekday night: Monday-Friday 18:00-07:59 the next day
- Weekend night: Saturday-Sunday 18:00-07:59 the next day
- Outcome
The primary outcome will be acute hospital mortality, defined as death before ultimate discharge from acute hospital. 4. Key confounders
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 16 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients (age 16 years or older)
- •Unplanned admission to the critical care unit (i.e. excluding admissions from theatre following elective or scheduled surgery, planned local medical admissions, planned transfers and repatriations)
排除标准
- •Readmission of the same patient to the critical care unit during the same acute hospital stay
- •Transfer from another critical care unit
- •Transfer from another acute hospital
- •Admission for organ donation
- •Missing time of admission
- •Missing acute hospital outcome
- •Missing key confounders (age, location prior to admission, primary reason for admission, all physiology)
结局指标
主要结局
Acute hospital mortality
时间窗: Discharge from acute hospital, an average of 22 days
Death before ultimate discharge from acute hospital
次要结局
未报告次要终点
研究者
David Harrison
Senior Statistician
Intensive Care National Audit & Research Centre