Treatment of Multiple Adjacent Gingival Recessions With Coronally Advanced Flap in Combination With Platelet-Rich Fibrin: A Split-Mouth Study
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Root Coverage
- Sponsor
- Marmara University
- Enrollment
- 12
- Primary Endpoint
- Percentage of Root Coverage
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
The aim of this study was to evaluate the clinical outcomes of platelet- rich fibrin and coronally advanced flap technique in the treatment of multiple gingival recessions in comparison with connective tissue graft technique.
Detailed Description
Aim of this study was to evaluate the clinical outcomes of platelet rich fibrin (PRF)+coronally advanced flap (CAF) technique in the treatment of multiple gingival recessions in comparison with connective tissue graft (CTG)+CAF technique.12 patients with bilateral Miller Class I multiple gingival recessions were treated with PRF+CAF (test group) and CTG+CAF (control group) technique in a split-mouth study design. Probing depth, recession depth (RD), clinical attachment level (CAL), recession width, position of gingival margin, papilla width, keratinized tissue height (KTH), keratinized tissue thickness (KTT) were measured at baseline and 3, 6 and 12 months after surgery. Root coverage (RC) and complete root coverage (CRC) ratios were evaluated post-operatively.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients had at two quadrants, adjacent Miller Class I and at least 2 mm or deeper recessions
- •Full mouth plaque score 20% and Full mouth bleeding on probing 10%
- •no active periodontal disease,
- •involving incisors, canines and premolars,
- •age ≥ 18 years
Exclusion Criteria
- •Patients with general diseases which could affect healing process,
- •Patients had undergone periodontal surgery during the pervious 24 months on the involved sites,
- •pregnant or breastfeeding women
- •endodontic lesions or non-detectable cemento-enamel junctions at experimental teeth
Outcomes
Primary Outcomes
Percentage of Root Coverage
Time Frame: 12 months
The percentage of root coverage was calculated according to the preoperative recession depth to postoperative recession depth.
Secondary Outcomes
- Change from Baseline Keratinized Tissue Width at 3 months(3 months)
- Complete Root Coverage(12 months)
- Change from Baseline Keratinized Tissue Width at 6 months(6 months)
- Change from Baseline Gingival Thickness at 12 months(12 months)
- Change from Baseline Gingival Thickness at 3 months(3 months)
- Change from Baseline Gingival Thickness at 6 months(6 months)
- Change from Baseline Keratinized Tissue Width at 12 months(12 months)