The Evaluation Clinical Results of Coronally Advanced Flap With Platelet Rich Fibrin
- Conditions
- Root Coverage
- Interventions
- Procedure: Platelet rich fibrin and coronally advanced flapProcedure: Connective tissue graft and coronally advanced flap
- Registration Number
- NCT04942821
- Lead Sponsor
- Marmara University
- Brief Summary
The aim of this study was to evaluate the clinical outcomes of platelet- rich fibrin and coronally advanced flap technique in the treatment of multiple gingival recessions in comparison with connective tissue graft technique.
- Detailed Description
Aim of this study was to evaluate the clinical outcomes of platelet rich fibrin (PRF)+coronally advanced flap (CAF) technique in the treatment of multiple gingival recessions in comparison with connective tissue graft (CTG)+CAF technique.12 patients with bilateral Miller Class I multiple gingival recessions were treated with PRF+CAF (test group) and CTG+CAF (control group) technique in a split-mouth study design. Probing depth, recession depth (RD), clinical attachment level (CAL), recession width, position of gingival margin, papilla width, keratinized tissue height (KTH), keratinized tissue thickness (KTT) were measured at baseline and 3, 6 and 12 months after surgery. Root coverage (RC) and complete root coverage (CRC) ratios were evaluated post-operatively.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 12
- Patients had at two quadrants, adjacent Miller Class I and at least 2 mm or deeper recessions
- Full mouth plaque score 20% and Full mouth bleeding on probing 10%
- no active periodontal disease,
- involving incisors, canines and premolars,
- age ≥ 18 years
- Patients with general diseases which could affect healing process,
- smokers
- Patients had undergone periodontal surgery during the pervious 24 months on the involved sites,
- pregnant or breastfeeding women
- endodontic lesions or non-detectable cemento-enamel junctions at experimental teeth
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Platelet rich fibrin and coronally advanced flap Platelet rich fibrin and coronally advanced flap Coronally advanced flap and platelet rich fibrin were used in treatment arms. Connective tissue graft and coronally advanced flap Connective tissue graft and coronally advanced flap Coronally advanced flap and connective tissue graft were used in treatment arms.
- Primary Outcome Measures
Name Time Method Percentage of Root Coverage 12 months The percentage of root coverage was calculated according to the preoperative recession depth to postoperative recession depth.
- Secondary Outcome Measures
Name Time Method Change from Baseline Keratinized Tissue Width at 3 months 3 months Width of keratinized tissue at mid-buccal point measured from free gingival margin to mucogingival junction
Complete Root Coverage 12 months Complete root coverage was calculated according to measurement of the pre and post operative gingival margin which was above the enamel-sement junction.
Change from Baseline Keratinized Tissue Width at 6 months 6 months Width of keratinized tissue at mid-buccal point measured from free gingival margin to mucogingival junction
Change from Baseline Gingival Thickness at 12 months 12 months Gingival thickness at mid-buccal aspect measured at the center of keratinized tissue.
Change from Baseline Gingival Thickness at 3 months 3 months Gingival thickness at mid-buccal aspect measured at the center of keratinized tissue.
Change from Baseline Gingival Thickness at 6 months 6 months Gingival thickness at mid-buccal aspect measured at the center of keratinized tissue.
Change from Baseline Keratinized Tissue Width at 12 months 12 months Width of keratinized tissue at mid-buccal point measured from free gingival margin to mucogingival junction