Treatment of Multiple Adjacent Gingival Recessions With Coronally Advanced Flap in Combination With Platelet-Rich Fibrin: A Split-Mouth Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 主要终点
- Percentage of Root Coverage
研究概览
简要总结
The aim of this study was to evaluate the clinical outcomes of platelet- rich fibrin and coronally advanced flap technique in the treatment of multiple gingival recessions in comparison with connective tissue graft technique.
详细描述
Aim of this study was to evaluate the clinical outcomes of platelet rich fibrin (PRF)+coronally advanced flap (CAF) technique in the treatment of multiple gingival recessions in comparison with connective tissue graft (CTG)+CAF technique.12 patients with bilateral Miller Class I multiple gingival recessions were treated with PRF+CAF (test group) and CTG+CAF (control group) technique in a split-mouth study design. Probing depth, recession depth (RD), clinical attachment level (CAL), recession width, position of gingival margin, papilla width, keratinized tissue height (KTH), keratinized tissue thickness (KTT) were measured at baseline and 3, 6 and 12 months after surgery. Root coverage (RC) and complete root coverage (CRC) ratios were evaluated post-operatively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients had at two quadrants, adjacent Miller Class I and at least 2 mm or deeper recessions
- •Full mouth plaque score 20% and Full mouth bleeding on probing 10%
- •no active periodontal disease,
- •involving incisors, canines and premolars,
- •age ≥ 18 years
排除标准
- •Patients with general diseases which could affect healing process,
- •Patients had undergone periodontal surgery during the pervious 24 months on the involved sites,
- •pregnant or breastfeeding women
- •endodontic lesions or non-detectable cemento-enamel junctions at experimental teeth
结局指标
主要结局
Percentage of Root Coverage
时间窗: 12 months
The percentage of root coverage was calculated according to the preoperative recession depth to postoperative recession depth.
次要结局
- Change from Baseline Keratinized Tissue Width at 3 months(3 months)
- Complete Root Coverage(12 months)
- Change from Baseline Keratinized Tissue Width at 6 months(6 months)
- Change from Baseline Gingival Thickness at 12 months(12 months)
- Change from Baseline Gingival Thickness at 3 months(3 months)
- Change from Baseline Gingival Thickness at 6 months(6 months)
- Change from Baseline Keratinized Tissue Width at 12 months(12 months)