NCT02394860终止不适用
Influence of Periodontal Diseases on Hemodynamic and Molecular Vascular Parameters in Patients Suffering of Hypertension
University Hospital, Strasbourg, France1 个研究点 分布在 1 个国家目标入组 76 人开始时间: 2015年4月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 76
- 试验地点
- 1
- 主要终点
- Measuring the thickness of the intima-media
研究概览
简要总结
The aim of this study is to assess the influence of the severity of chronic periodontitis on hemodynamic parameters in hypertensive patients.Secondary purposes of this protocol is to identify evolution of several biomarkers and correlate the clinical situation with oral microflora.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •-Men- >40 years
- •moderate and severe generalized chronic periodontitis
- •Former diagnosis of hypertension
- •>12 teeth
排除标准
- •>70 years
- •smokers (>10 cig/day)
- •body mass index>30
- •Need of antibioprophylaxis
- •Medical treatment including anti-inflammatory drugs and/or antibiotics
- •Refractory form of hypertension- aggressive periodontitis
结局指标
主要结局
Measuring the thickness of the intima-media
时间窗: 15 days
次要结局
- Evaluation of anatomical changes that may occur at the arterial level(Within 15 days after inclusion)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Effect of gum treatment on endotoxin blood levels (bacterial product) in women with gum disease (pyorrhea).CTRI/2011/05/001766Shaju Jacob P16
已完成
不适用
Influence of Periodontal Treatment on Systemic Inflammatory MediatorsCoronary Heart DiseasePeriodontal DiseaseNCT01201746Sheikh Zayed Federal Postgraduate Medical Institute317
终止
不适用
Study of Periodontitis and Blood Stream Infection in AML Patients Receiving ChemotherapyAcute Myeloid LeukemiaNCT04858594Masonic Cancer Center, University of Minnesota3
Unknown
不适用
Perio Treatment & Cerebrovascular FunctionPeriodontitisNCT05506917University of Santiago de Compostela30
已完成
不适用
Impact of Gum Infection on Heart DiseaseCardiovascular DiseasePeriodontal DiseaseNCT00093236Boston University174