A comparison of two methodes for pastoperative paintreatment after knee replacement. Pharmacokinetics and clinical effect of femoral block and local infiltration of the operation area of ropivacaine.
- Conditions
- Knee replacement Postoperative paintreatment
- Registration Number
- EUCTR2006-002581-19-SE
- Lead Sponsor
- ina Olofsson
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Adult males or females ASA 1-3 undergoing spinal anesthesia for elective knee replacement. Have sign informed consent.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
Allergy for NSAID or local anaesthetic. Bleeding disorders Demens or psychiatric disorder. Patints who refusesto partisipart. Av-block II or III Hepato renal disorders ulcus duodeni or ventriculi
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: Quality control of paintreatment after knee replacement. Two methodes will bee compared, Femoral block or local infiltration in the operating area during surgery. ;Secondary Objective: Plasmaconcentration of Ropivacaine and its pharmacokinetics during first 12 hours after surgery.;Primary end point(s): Vas registration for pain
- Secondary Outcome Measures
Name Time Method