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Safety and Immunogenicity of a Quadrivalent Meningococcal Tetanus Protein Conjugate Vaccine in Toddlers

Phase 1
Completed
Conditions
Meningitis
Meningococcal Infection
Interventions
Biological: Meningococcal Polysaccharide Tetanus Protein Conjugate
Dietary Supplement: Meningococcal polysaccharide group C conjugated
Registration Number
NCT00631995
Lead Sponsor
Sanofi Pasteur, a Sanofi Company
Brief Summary

This study is aimed at studying quadrivalent meningococcal (A, C, Y, and W-135) Tetanus Protein Conjugate Vaccine (TetraMen-T) formulations in Toddlers.

Primary Objectives: Safety and Immunogenicity:

To describe the safety and immunogenicity profiles of:

* A single dose of each formulation of TetraMen-T vaccine

* A single dose of NeisVac-C® vaccine.

Detailed Description

The study is designed to evaluate the safety profile and the immunogenicity response after a single dose of TetraMen-T in toddlers.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
360
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Group 4Meningococcal Polysaccharide Tetanus Protein Conjugate-
Group 2Meningococcal Polysaccharide Tetanus Protein Conjugate-
Group 5Meningococcal Polysaccharide Tetanus Protein Conjugate-
Group 6Meningococcal polysaccharide group C conjugated-
Group 1Meningococcal Polysaccharide Tetanus Protein Conjugate-
Group 3Meningococcal Polysaccharide Tetanus Protein Conjugate-
Primary Outcome Measures
NameTimeMethod
To provide information concerning the safety and immunogenicity after administration of TetraMenT30 days after each injection
Secondary Outcome Measures
NameTimeMethod
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