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临床试验/CTRI/2020/11/028895
CTRI/2020/11/028895尚未招募不适用

Assessment of expiratory muscle dysfunction in critically ill patients using abdominal ultrasound and association with basal lung atelectasis, diaphragmatic excursion and weaning success – a cross-sectional study.

Vedaghosh Amara1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2020年11月16日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
80
试验地点
1
主要终点
Assessment of expiratory muscle function, diaphragmatic excursion and basal lung atelectasis with ultrasound during the course of intensive care stay.

研究概览

简要总结

Expiratory muscles are an important component of respiratory function and muscle pump, especially in critically ill patients. But, it is often neglected by the clinician, who focuses mostly on the inspiratory muscles like diaphragm. The expiratory muscle which are crucial for successful weaning from ventilatory support are rectus abdominis, internal oblique, external oblique and transverse abdominis muscles. The thickness of these muscles should follow a particular order for us to ensure that expiratory muscles are functioning properly. The order of thickness is rectus abdominis>internal oblique>external oblique>transverse abdominis. We aim to analyze this muscle thickness pattern using bedside ultrasound in ICU patients whenever they are being weaned from either non-invasive ventilation or invasive ventilation. So, we will be performing the bedside ultrasound on those weaning days, and we will record the expiratory muscle thickness order , lung ultrasound findings and even the inspiratory muscle (diaphragmatic) excursion. We will correlate these findings to assess whether this has a positive predictive value in spontaneous breathing success. If a correlation is found, the expiratory muscle ultrasound can form a part of future weaning protocols and criteria.

We are prospectively going to recruit 80 patients with the given inclusion and exclusion criteria for the study over a period of one year

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • •Patients on Oxygen Support with either invasive ventilation or Non Invasive ventilation.

排除标准

  • •(i)Patients with abdominal trauma causing damage to the abdominal wall and distortion of the anatomy.
  • •(ii)Patients with localized fluid collections, hernias (ventral hernias, Spigelian hernias, incisional hernia, femoral hernia, endometriosis, abdominal wall hematoma, inguinal masses.

结局指标

主要结局

Assessment of expiratory muscle function, diaphragmatic excursion and basal lung atelectasis with ultrasound during the course of intensive care stay.

时间窗: time to spontaneous breathing trial either success or failure or 7 days whichever is earlier.

次要结局

  • outcome of icu stay(28 days)

研究者

发起方
Vedaghosh Amara
申办方类型
Other [self]

研究点 (1)

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