Investigating the effects of conventional and high-definition transcranial direct current stimulation (tDCS) on working memory and neuroplasticity in healthy volunteers
Completed
- Conditions
- europlasticity in healthy volunteersNeuroplasticity in healthy volunteersMental Health - Studies of normal psychology, cognitive function and behaviourNeurological - Studies of the normal brain and nervous system
- Registration Number
- ACTRN12614000652673
- Lead Sponsor
- Monash Univeristy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
1) Right-handed adults who have the capacity to provide informed consent.
2) Have no personal history of psychiatric or neurological illness.
Exclusion Criteria
1) Anyone suffering from an unstable medical condition, neurological or psychiatric disorder or any history of a seizure disorder or who are currently pregnant or breastfeeding.
2) Anyone with any metallic implants in the head, a pacemaker, cochlear implant medication pump or other electronic device.
3) Anyone currently taking any psychoactive medications.
4) Professional drivers are not able to participate due to the, albeit relatively low, risk of seizure as this could affect their employment.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method -back task accuracy and reaction time[Two separate time-points for each session:<br>a) directly after tDCS treatment<br>b) 30 minutes after tDCS treatment ];TMS-EEG evoked potential amplitudes[a) Immediately after tDCS treatment<br>b) 30 minutes following tDCS treatment]
- Secondary Outcome Measures
Name Time Method EEG oscillations (theta ERS and alpha ERD) [Two timepoints for each session. EEG oscilations recorded during n-back task:<br><br>a) Immediately after tDCS treatment<br>b) 30 minutes following tDCS treatment]