Metamizole versus NSAID, two painkillers for painrelief at home after day surgery: a double-blind randomized controlled trial

• Conditions: Pain after ambulatory surgery; Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]

• Registration Number: EUCTR2015-003987-35-BE
• Lead Sponsor: JESSA Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-10-07
• Last Update Posted: 18 January 2016

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

- Patients aged between 18 and 70 years
- ASA classification 1,2 or 3
- one of the following ambulatory surgical procedures:
- anal surgery (anal fissura or haemmorrhoids)
- arthroscopy knee
- arthroscopy shoulder with interscalenus block
- inguinal hernia repair

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 170
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 30

Exclusion Criteria

not meeting inclusion criteria, cognitive impairment or no understanding of the dutch language, preoperative pharmacologic pain treatment with opioids, chronic pain (fibromyalgia, CRPS, etc), allergy to or a contraindication for taking the study medication (e.g. paracetamol, metamizole, ibuprofen or another NSAID), porphyria, pregnancy, lactation, history of severe renal, hepatic, pulmonary, or cardiac failure, current symptoms or history of gastrointestinal bleeding, ileus, chronic obstipation, history of substance abuse, or use of medication with a suppressive effect on the central nervous system, hypotension, hematological disaese, use of anti-rheumatic drugs, rhinosinusitis or nasal polyposis, Glucose-6-phosphate dehydrogenase deficiency, fever or other signs of infection

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified