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Clinical Trials/CTRI/2025/12/098414
CTRI/2025/12/098414
Not yet recruiting
Not Applicable

Impact of Doctor-Patient Communication on Post Traumatic Growth: Mediating Role of Intolerance of Uncertainty in Ovarian Cancer Patients

Ananya Agrawal1 site in 1 country134 target enrollmentStarted: December 14, 2025Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Ananya Agrawal
Enrollment
134
Locations
1
Primary Endpoint
To find out how communication between doctors and patients affects post traumatic growth in women with ovarian cancer, and how their ability to handle uncertainty influences this link.

Overview

Brief Summary

Aim: To examine how doctor patient communication and intolerance of uncertainty influence post traumatic growth in individuals with ovarian cancer.

Objectives:

  1. To assess the impact of patients perception of doctor patient communication on post traumatic growth.
  2. To examine whether intolerance of uncertainty mediates the relationship between communication perceptions and post traumatic growth.

Instruments:

  • Sociodemographic Details Sheet: Includes age, gender, education, occupation, years of treatment, cancer stage and type, chronic medical and psychiatric conditions.
  • Patient Centred Communication Cancer 36 PCC Ca 36: Assesses patients perceptions of communication in cancer care across six domains using 36 items rated on a 5 point Likert scale. Higher scores indicate better perceived communication.
  • Intolerance of Uncertainty Scale IUS: A 27 item scale measuring prospective and inhibitory anxiety related to uncertainty. Rated on a 5 point Likert scale, with higher scores indicating greater intolerance of uncertainty.
  • Post Traumatic Growth Inventory PTGI: A 21 item scale assessing positive psychological changes across five domains. Rated on a 6 point scale. Higher scores indicate greater post traumatic growth.

Procedure: Institutional and ethics approvals will be obtained followed by Clinical Trial Registry of India registration. Recruitment will occur in oncology and gynaecology OPDs through flyers and in person contact. Tools will be translated by certified professionals. Eligible participants will provide informed consent and complete sociodemographic details and standardised scales. Data will be entered into SPSS for descriptive and inferential analysis, and AMOS will be used for mediation analysis through structural equation modelling. Data interpretation will be done by the research team.

Data Analysis: SPSS and AMOS will be used.

Statistical Tests:

  • Descriptive statistics mean and standard deviation
  • Pearson correlation
  • Simple linear regression
  • Structural equation modelling SEM

Study Design

Study Type
Observational

Eligibility Criteria

Ages
18.00 Year(s) to 90.00 Year(s) (—)
Sex
Female

Inclusion Criteria

  • Diagnosed with Ovarian Cancer, Minimum 1 year post diagnosis during treatment, Currently recieving treatment at Manipal and can understand the questions, women above 18 years.

Exclusion Criteria

  • Presence of severe psychiatric conditions, Recurrent or terminal cancer diagnosis, Prior diagnosis of another major chronic illness.

Outcomes

Primary Outcomes

To find out how communication between doctors and patients affects post traumatic growth in women with ovarian cancer, and how their ability to handle uncertainty influences this link.

Time Frame: 8 months

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Ananya Agrawal
Sponsor Class
Other [Allied Health Sciences College ]
Responsible Party
Principal Investigator
Principal Investigator

Ananya Agrawal

Manipal College of Health Professions (MCHP), Manipal Academy of Higher Education

Study Sites (1)

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