Relationship between oxytocin and borderline personality disorder

Not Applicable

• Conditions: Mental Disorders; Borderline Personality Disorder; F03.675.100

• Registration Number: RBR-2rnbw6
• Lead Sponsor: Faculdade de Medicina de Ribeirão Preto

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-10-20
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

women over 18 years of age; literate; of childbearing age; in contraceptive use for more than six months; who agree to participate by signing the Free and Informed Consent Form approved by the Ethics and Research Committee of the HCFMRP; who agree to measure levels of estrogen and progesterone to delineate the menstrual cycle; that are in the follicular phase of the cycle. For inclusion in the TPB group, women should have: a diagnosis of BPD performed using the criteria established by the DSM-5 classification; being in outpatient treatment.
In the control group, only women with no history of current or previous psychiatric disorder evaluated by SCID-5 will be admitted. In the study of continuous use, they will be admitted to women with BPD of childbearing age, over 18 years of age, without pretense of becoming pregnant within the next 6 months, who are literate and who agree to participate and sign the ICF approved by the HCFMRP Ethics and Research Committee. In addition, in this group, only women with a diagnosis of BPD will be accepted, based on the criteria established by the classification of DSM-5 (APA, 2014), in outpatient treatment; who agree not to modify their treatments during the study period.

Exclusion Criteria

Participants will be excluded from the study if they refer to clinical diseases that have a major impact on the functioning of the organism, such as degenerative diseases, neurological diseases, cancers, hematological, pulmonary, renal, hepatic and cardiovascular diseases; pregnant or lactating women.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the associations between OXT and TPB thorght endogenous levels of OXT and intranasal OXT.