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Clinical Trials/NCT06291090
NCT06291090
Completed
Not Applicable

In Hospital Treatment of Opioid Use Disorder: Clinician Perspectives and Current Practices

University of Colorado, Denver2 sites in 1 country400 target enrollmentJanuary 18, 2023

Overview

Phase
Not Applicable
Intervention
OUD treatment intervention
Conditions
Opioid Use Disorder
Sponsor
University of Colorado, Denver
Enrollment
400
Locations
2
Primary Endpoint
Change in buprenorphine prescribing at hospital discharge
Status
Completed
Last Updated
yesterday

Overview

Brief Summary

The investigators implemented a multi-site hospital-based opioid use disorder (OUD) treatment intervention across 12 hospitals in Colorado to address an OUD treatment gap among hospitalized adults with OUD.

Detailed Description

The investigators implemented a multi-site hospital-based opioid use disorder (OUD) treatment intervention across 12 hospitals in Colorado to address an OUD treatment gap among hospitalized adults with OUD. The intervention included nurse driven universal screening for unhealthy substance use with a social work referral for a brief intervention when indicted, electronic health record-embedded protocols to assess for opioid withdrawal and to direct buprenorphine initiation, methadone orders for opioid withdrawal symptoms, and embedded links for post discharge addiction treatment referral. It also included clinician education and nursing education via video conference or in-person lectures. The intervention was supported by the health system Chief Medical Officer and involved subject matters expertise and representation from nursing leaders, social work leaders, and hospital medicine leaders. Outcomes assess include a pre/post implementation assessment of 1) change in buprenorphine prescribed in hospital and 2) discharge, 3) change in naloxone prescribed, 4) change in hospital based methadone prescribing, and 5) change in average clinical opioid withdrawal scale (COWS) score. investigators also assessed a pre/post survey of hospitalists physicians and advanced practice providers to assess their perception of hospital based OUD treatment provision.

Registry
clinicaltrials.gov
Start Date
January 18, 2023
End Date
May 1, 2025
Last Updated
yesterday
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Physicians, advanced practice providers, social workers, and nurses who work at any affiliated hospitals

Exclusion Criteria

  • Not provided

Arms & Interventions

OUD intervention

Participants received education on the diagnosis and management of OUD, have access to protocols to walk them through assessment of OUD using Diagnostic and Statistical Manual, fifth Edition (DSM)-5, COWS score to calculate severity of opioid withdrawal, buprenorphine or methadone initiation with pre-populated orders, and clickable links for OUD treatment referral post discharge.

Intervention: OUD treatment intervention

Outcomes

Primary Outcomes

Change in buprenorphine prescribing at hospital discharge

Time Frame: Calculate monthly prescribing rates over a three year time frame (including pre and post implementation) to assess for change

Change in rate of buprenorphine prescribing at hospital discharge among patients with OUD before and after intervention implementation

Secondary Outcomes

  • Change in rates of methadone prescribing during hospitalization(Calculate monthly prescribing rates over a three year time frame (including pre and post implementation) to assess for change)

Study Sites (2)

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