Comparison the Effects of Intrathecal Meperidine and Dexmedetomidine added to Bupivacaine in the Woman Undergoing Cesarean Section.
Phase 2
- Conditions
- Delivery by elective caesarean sectioncesarean.
- Registration Number
- IRCT2014100814372N4
- Lead Sponsor
- Shiraz University of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 90
Inclusion Criteria
pregnant women ASA I-II; singleton pregnancies; elective Caesarean section; term neonate; no contraindication for spinal anesthesia.
Exclusion criteria :heart diseases; liver diseases; renal failure; coagulopathy; sensitivity to drugs; lack of consent; spinal anesthesia contraindication;a history of seizures; neurological diseases;(IUGR)
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The duration of sensory block. Timepoint: Perioperative every 20 min and Post-operative 10 min after arrival to the recovery room. Method of measurement: Pinprick.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms by which intrathecal meperidine and dexmedetomidine enhance bupivacaine's analgesic effects in elective cesarean sections?
How does the combination of intrathecal meperidine and dexmedetomidine compare to standard-of-care analgesia in post-cesarean pain management?
What biomarkers could predict differential response to intrathecal meperidine versus dexmedetomidine in caesarean patients?
What are the potential adverse events associated with intrathecal administration of meperidine and dexmedetomidine in obstetric anesthesia?
How do intrathecal adjuvants like meperidine and dexmedetomidine compare to other alpha-2 agonists or opioids in cesarean analgesia efficacy?